Allergic Contact Dermatitis to Low Molecular Weight Allergens in the Chicken
| Autor: | Henry C. Maguire, William P. Weidanz, R.G. Rank |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Male
Immunology Picryl Chloride Dermatitis Contact medicine.disease_cause Wattle (anatomy) Picryl chloride Oxazolone chemistry.chemical_compound Allergen medicine Animals Immunology and Allergy Allergic contact dermatitis Sensitization Dimethyl sulfoxide General Medicine Allergens medicine.disease Molecular Weight medicine.anatomical_structure chemistry Dinitrofluorobenzene Previously treated Chickens |
| Zdroj: | International Archives of Allergy and Immunology. 50:737-744 |
| ISSN: | 1423-0097 1018-2438 |
| Popis: | We have produced allergic contact dermatitis (ACD) to low molecular weight allergens in the chicken. Sensitization was induced by the application of a high concentration of allergen to a site on the comb previously treated with dimethyl sulfoxide. Challenge, which was made on the wattle with a nonirritating concentration of allergen, resulted in a dermatitis that was grossly and histologically similar to ACD in mammals. Chickens sensitized to oxazolone reacted to that allergen and not to picryl chloride, and conversely. This model provides a unique system wherein to study the T-cell and B-cell contributions to the generation, maintainance and expression of the ACD response. |
| Databáze: | OpenAIRE |
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