Osmoprotection of Escherichia coli by ectoine: uptake and accumulation characteristics
| Autor: | Karine Gloux, R. Talibart, Mohamed Jebbar, Carlos Blanco, Théophile Bernard |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Proline
Osmotic shock Biology Ectoine medicine.disease_cause Microbiology Ectoine transport chemistry.chemical_compound Betaine Escherichia coli medicine Molecular Biology chemistry.chemical_classification Osmolar Concentration Amino Acids Diamino Ectoine synthase Biological Transport Amino acid chemistry Biochemistry Genes Bacterial Glycine biology.protein Carrier Proteins Research Article |
| Zdroj: | Europe PubMed Central Scopus-Elsevier |
| ISSN: | 1098-5530 0021-9193 |
| DOI: | 10.1128/jb.174.15.5027-5035.1992 |
| Popis: | Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a cyclic amino acid, identified as a compatible solute in moderately halophilic bacteria. Exogenously provided ectoine was found to stimulate growth of Escherichia coli in media of inhibitory osmotic strength. The stimulation was independent of any specific solute, electrolyte or nonelectrolyte. It is accumulated in E. coli cells proportionally to the osmotic strength of the medium, and it is not metabolized. Its osmoprotective ability was as potent as that of glycine betaine. The ProP and ProU systems are both involved in ectoine uptake and accumulation in E. coli. ProP being the main system for ectoine transport. The intracellular ectoine pool is regulated by both influx and efflux systems. |
| Databáze: | OpenAIRE |
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