| Popis: |
Atypical chronic myeloid leukemia BCR-ABL negative is rare myelodysplastic syndrome/myeloproliferative neoplasm for which there is no current standard of therapy. Patients with aCML had pronounced immature granulocytosis and granulocytotic dysplasia in their blood smears. We admitted a 60-year-old man with splenomegaly, hyperleukocytosis, anemia, and thrombocytopenia; after cytology, cytogenetic, and molecular biology analyses of bone marrow, we diagnosed aCML using 2016 World Health Organization classification. Chemotherapy was used to treat the patient at first, but the patient’s anemia worsened. This prompted a modification in treatment. |
