Criteria for Excision of Suspicious Calcifications Using the Breast Lesion Excision System (BLES)
| Autor: | Constantinos G Zografos, Afrodite Nonni, Alexandra Christou, Dimitra Koulocheri, Vassilis Koutoulidis, Georgios Zografos |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
education.field_of_study
medicine.medical_specialty Breast lesion excision system (BLES) Comedo medicine.diagnostic_test business.industry Biopsy Population Neoplasms. Tumors. Oncology. Including cancer and carcinogens General Medicine medicine.disease Lesion Breast cancer Comedo Necrosis Atypia Medicine Histopathology Radiology medicine.symptom Calcifications business education RC254-282 |
| Zdroj: | Archives of Breast Cancer (2021) |
| Popis: | Background: The aim of the study was to retrospectively evaluate possible imaging and histopathology criteria that can be used in a clinical basis to assess the success of excision of suspicious calcifications using the breast lesion excision system (BLES).Methods: We investigated 400 BLES stereotactic biopsies of suspicious calcifications with the mean size of 15.38 mm (st. dev.= 13.579 mm, range 3-78 mm) using a 20 mm probe performed in our department between January 2014 and 2016. The mean age of our population was 58.5 years old (range 39-78 years). The pathology results of BLES specimens were compared with the final surgical results to assess excision success rates. Possible imaging and histopathology criteria for removal were statistically analyzed (mammographic size, disease free margins, grade, comedo phenotype, molecular type).Results: The results showed that 90/400 (22.5%) biopsies were cancers (80% DCIS) and 38/400 were lesions with cell atypia (9.5%) of which 29/38 had subsequent surgery and were included in the study. Excision was achieved in 31/90 cancers (34.4%) and in 23/29 lesions with cell atypia (76.3%). The imaging and histopathology criteria for BLES excision that could be potentially clinically assessed were the initial mammographic size (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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