Rapid awareness and transmission of severe acute respiratory syndrome in Hanoi French Hospital, Vietnam
| Autor: | Naoto Keicho, Teruo Kirikae, Nguyen Chi Phi, Tadatoshi Kuratsuji, Hiroshi Nishiura, Hoang Thuy Long, Le Dang Ha, Takehiko Sasazuki, Roy M. Anderson, Hideki Yanai, Tran Quy, Vo Van Ban |
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| Předmět: |
medicine.medical_specialty
media_common.quotation_subject Severe Acute Respiratory Syndrome Clothing Disease Outbreaks law.invention Hygiene law Virology Epidemiology medicine Humans media_common Analysis of Variance Cross Infection Models Statistical business.industry Case-control study Outbreak Odds ratio Confidence interval Surgery Infectious Diseases Transmission (mechanics) Severe acute respiratory syndrome-related coronavirus Vietnam Case-Control Studies Emergency medicine Parasitology business Basic reproduction number Hand Disinfection |
| Zdroj: | Scopus-Elsevier |
| Popis: | A case-control study was conducted to examine the relationship between severe acute respiratory syndrome (SARS) and the time-dependent precautionary behaviors taken during an outbreak of SARS in Hanoi French Hospital (HFH), Vietnam. Masks (odds ratio [OR] = 0.3; 95% confidence interval [CI]: 0.1, 0.7) and gowns (OR = 0.2; 95% CI: 0.0, 0.8) appeared to prevent SARS transmission. The proportion of doctors and nurses who undertook each measure significantly improved (chi(2) = 9.8551, P = 0.043) after the onset of secondary cases. The impact of individual behaviors on an outbreak was investigated through mathematical approaches. The reproduction number decreased from 4.1 to 0.7 after notification. The basic reproduction number was estimated, and the use of masks alone was shown to be insufficient in containing an epidemic. Intuitive results obtained by means of stochastic individual-based simulations showed that rapid improvements in behavior and isolation would increase the probability of extinction. |
| Databáze: | OpenAIRE |
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