Moxibustion for prehypertension and stage I hypertension: a pilot randomized controlled trial
| Autor: | Sun-Mi Choi, Ji-Eun Park, Tae-Han Yook, Ojin Kwon, Kyung Min Shin, Jong Uk Kim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
BP
blood pressure medicine.medical_specialty PSQI Pittsburgh Sleep Quality Index Moxibustion BMI body mass index medicine.medical_treatment 0211 other engineering and technologies DBP diastolic blood pressure SRI-MF Modified Form of the Stress Response Inventory EQ-5D EuroQol-5 Dimensions 02 engineering and technology HRV heart rate variability Prehypertension law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine 021105 building & construction medicine Acupuncture RCT randomized controlled trial Adverse effect Stroke lcsh:Miscellaneous systems and treatments SAE serious adverse event business.industry SBP systolic blood pressure NDI neck disability index MD mean difference medicine.disease lcsh:RZ409.7-999 FSS Fatigue Severity Scale 030205 complementary & alternative medicine CI confidence interval Clinical research Blood pressure Complementary and alternative medicine Hypertension Original Article business AE adverse event |
| Zdroj: | Integrative Medicine Research, Vol 8, Iss 1, Pp 1-7 (2019) Integrative Medicine Research |
| ISSN: | 2213-4220 |
| Popis: | Background Prehypertension and hypertension are associated with cardiovascular disease, ischemic heart disease, and stroke morbidity. The purpose of this study is to evaluate the effectiveness and safety of moxibustion in patients with prehypertension or hypertension. Methods Forty-five subjects with prehypertension or stage I hypertension were randomized into three groups: moxibustion treatment group A (2 sessions/week for 4 weeks), moxibustion treatment group B (3 sessions/week for 4 weeks), and control group (nontreated group). The primary outcome measure was the change in blood pressure after 4 weeks of treatment. Safety was assessed at every visit. Results There were no significant differences in systolic blood pressure (SBP) or diastolic blood pressure (DBP) among three groups after 4 weeks of treatment (p = 0.4798 and p = 0.3252, respectively). In treatment group B, there was a significant decrease in SBP and DBP from baseline to 4 weeks of treatment (mean difference (MD) −9.55; p = 0.0225, MD −7.55; p = 0.0098, respectively). There were no significant differences among groups in secondary outcome measures after 4 weeks of treatment. Six adverse events (AEs) in the treatment group A and 12 AEs in the treatment group B occurred related to the moxibustion treatment. Conclusion In conclusion, the results of this study show that moxibustion (3 sessions/week for 4 weeks) might lower blood pressure in patients with prehypertension or stage I hypertension and treatment frequency might affect effectiveness of moxibustion in BP regulation. Further randomized controlled trials with a large sample size on prehypertension and hypertension should be conducted. Trial registration This study was registered with the ‘Clinical Research Information Service (CRIS)’, Republic of Korea (KCT0000469), and the protocol for this study was presented orally at the 15th International Council of Medical Acupuncture and Related Techniques (ICMART) in Athens, 25–27 May 2012. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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