Synthesis of 1,2,3-Triazines Using the Base-Mediated Cyclization of (Z)-2,4-Diazido-2-alkenoates

Autor: Ikuo Sasaki, Hideyuki Sugimura, Shiori Ichikawa, Eri Nagayama, Reika Takeuchi
Rok vydání: 2018
Předmět:
Zdroj: Organic Letters. 20:3434-3437
ISSN: 1523-7052
1523-7060
DOI: 10.1021/acs.orglett.8b01445
Popis: A highly efficient and convenient method for the synthesis of 6-aryl-1,2,3-triazine-4-carboxylate esters has been developed using readily accessible ( Z)-4-aryl-2,4-diazido-2-alkenoates. This reaction is performed under mildly basic conditions without the assistance of any transition metals or strong acid.
Databáze: OpenAIRE