Late Recovery of Parathyroid Function After Total Thyroidectomy: A Case-Control Study
| Autor: | Manel Sahún de la Vega, Juan J. Díez, Concepción Blanco Carrera, Carles Zafon, Orosia Bandrés, Miguel Paja, Amelia Oleaga, Julia Sastre, Emma Anda, Cristina Álvarez-Escolá, José Carlos Fernández-García, Sergio Donnay, Ana Megia, Eva Sanz, Begoña Pérez Corral, Elena Navarro, María Picallo, Beatriz Lecumberri, Pedro Iglesias, Juan C. Galofré, Marcel Sambo, Laura Manjón, Gloria Baena-Nieto, Piedad Santiago Fernández, Ana R Romero-Lluch, Cecilia Sánchez Ragnarsson |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Calcitriol Hypoparathyroidism Endocrinology Diabetes and Metabolism medicine.medical_treatment Clinical Biochemistry chemistry.chemical_element Late recovery Calcium Biochemistry Parathyroid Glands Endocrinology Postoperative Complications Internal medicine medicine Humans Pathological Retrospective Studies Total thyroidectomy business.industry Biochemistry (medical) Thyroidectomy Case-control study General Medicine Recovery of Function Middle Aged medicine.disease Surgery chemistry Spain Case-Control Studies Female business medicine.drug Follow-Up Studies |
| Zdroj: | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 53(10) |
| ISSN: | 1439-4286 |
| Popis: | The clinical characteristics of patients with postoperative hypoparathyroidism who recover parathyroid function more than 12 months after surgery have not been studied. We aimed to evaluate whether the intensity of replacement therapy with calcium and calcitriol is related to the late recovery of parathyroid function. We compared the demographic, surgical, pathological, and analytical features of two groups of patients: cases, i. e., late recovery patients (those who recover parathyroid function>1 year after thyroidectomy, n=40), and controls, i. e., patients with permanent hypoparathyroidism (n=260). Replacement therapy with calcium and calcitriol was evaluated at discharge of surgery, 3–6 months, 12 months, and last visit. No significant differences were found in clinical, surgical, pathological, or analytical characteristics between cases and controls. The proportion of cases who required treatment with calcium plus calcitriol at 12 months was significantly lower than that found in controls (p |
| Databáze: | OpenAIRE |
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