Which patients benefit from preoperative biliary drainage in resectable pancreatic cancer?
| Autor: | Sarah Blacker, Rajesh Kumar, Adam E Frampton, Mary Phillips, Nariman D. Karanjia, Tim D Pencavel, Rajiv P Lahiri, T.R. Worthington, A. Riga, Graham Pinn |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Resectable Pancreatic Cancer
Male medicine.medical_specialty medicine.medical_treatment Head of pancreas behavioral disciplines and activities 03 medical and health sciences 0302 clinical medicine Preoperative Care medicine Humans In patient Aged Retrospective Studies Biliary drainage Chemotherapy Hepatology business.industry General surgery Gastroenterology Bilirubin Jaundice Middle Aged Pancreaticoduodenectomy medicine.disease Pancreatic Neoplasms Malnutrition Jaundice Obstructive medicine.anatomical_structure 030220 oncology & carcinogenesis Drainage 030211 gastroenterology & hepatology Female medicine.symptom business |
| Zdroj: | Expert review of gastroenterologyhepatology. 15(8) |
| ISSN: | 1747-4132 |
| Popis: | Recent studies have indicated that preoperative biliary drainage (PBD) should not be routinely performed in all patients suffering from obstructive jaundice before pancreatic surgery. The severity of jaundice that mandates PBD has yet to be defined. The evaluated paper examines the impact of PBD on intra-operative, and post-operative outcomes in patients initially presenting with severe obstructive jaundice (bilirubin ≥250 μmol/L). In this key paper evaluation, the impact of PBD versus a direct surgery (DS) approach is discussed. The arguments for and against each approach are considered with regards to drainage associated morbidity and mortality, resection rates, survival and the impact of chemotherapy and malnutrition. Concentrating on resectable head of pancreas tumors, this mini-review aims to scrutinize the authors' recommendations, alongside those of prominent papers in the field. |
| Databáze: | OpenAIRE |
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