Long-term effects of respiratory syncytial virus (RSV) bronchiolitis in infants and young children
| Autor: | MCJ Kneyber, EW Steyerberg, R de Groot, HA Moll |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2000 |
| Předmět: |
Respiratory Sounds/etiology
Infant General Medicine Respiratory Syncytial Virus Infections Prognosis Asthma/etiology Asthma Child Preschool Respiratory Syncytial Virus Human Pediatrics Perinatology and Child Health Bronchiolitis/complications Bronchiolitis Humans Respiratory Syncytial Virus Child Preschool Respiratory Sounds Follow-Up Studies Randomized Controlled Trials as Topic Respiratory Syncytial Virus Infections/complications Human |
| Zdroj: | Acta Paediatrica. 89(6):654-660 |
| ISSN: | 0803-5253 |
| DOI: | 10.1111/j.1651-2227.2000.tb00359.x |
| Popis: | UNLABELLED: One of the major questions regarding long-term side effects of bronchiolitis by respiratory syncytial virus (RSV) is whether or not it induces asthma in later life. In this quantitative review, the data of 10 controlled studies are analysed. METHODS: Follow-up studies of RSV bronchiolitis published between January 1978 and December 1998 were identified through a MEDLINE search. Studies were selected if (i) postnatal age at the time of the initial illness was below 12 mo, (ii) all children were hospitalized for RSV bronchiolitis, (iii) the diagnosis RSV was virologically confirmed in all cases, and (iv) a control group was used. RESULTS: Six studies met all selection criteria. Up to 5 y of follow-up after RSV bronchiolitis in infancy, 40% of children reported wheezing as compared to only 11% in the control group (p or = 5 y of follow-up. However, no significant difference between the RSV bronchiolitis and the control group was observed regarding recurrent wheezing by 5 y of follow-up. No significant difference between the RSV bronchiolitis and the control group were found regarding a personal history of atopy, a family history of atopy and/or asthma. Therefore it seems unlikely that RSV bronchiolitis is a cause of atopic asthma in later life. |
| Databáze: | OpenAIRE |
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