Autor: |
Yaser Atlasi, Ron Smits, Riccardo Fodde, Andreas Kremer, Sabrina Roth, Pieter Sonneveld, Andrea Sacchetti, Mehrnaz Ghazvini, Patrick Franken, Rosalie Joosten |
Přispěvatelé: |
Developmental Biology, Pathology, Gastroenterology & Hepatology |
Rok vydání: |
2013 |
Předmět: |
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Zdroj: |
PLoS One (print), 8(9). Public Library of Science PLoS ONE, Vol 8, Iss 9, p e73872 (2013) PLoS ONE |
ISSN: |
1932-6203 |
Popis: |
Constitutive activation of the Wnt pathway leads to adenoma formation, an obligatory step towards intestinal cancer. In view of the established role of Wnt in regulating stemness, we attempted the isolation of cancer stem cells (CSCs) from Apc- and Apc/KRAS-mutant intestinal tumours. Whereas CSCs are present in Apc/KRAS tumours, they appear to be very rare ( |
Databáze: |
OpenAIRE |
Externí odkaz: |
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