Familial Resemblance for Loneliness
| Autor: | Abdel Abdellaoui, Dorret I. Boomsma, Irene Rebollo-Mesa, John T. Cacioppo, Marijn A. Distel, Catherine Derom, Gonneke Willemsen |
|---|---|
| Přispěvatelé: | Biological Psychology, Social Psychology, EMGO+ - Mental Health |
| Rok vydání: | 2010 |
| Předmět: |
Male
Netherlands Twin Register (NTR) Genotype Inheritance Patterns Twins 050109 social psychology Models Psychological Social Environment Affect (psychology) Developmental psychology Heritability 03 medical and health sciences SDG 3 - Good Health and Well-being Genetics medicine Humans Genetics(clinical) 0501 psychology and cognitive sciences Registries Social isolation GE interaction 10. No inequality Genetics (clinical) Ecology Evolution Behavior and Systematics Original Research 030304 developmental biology 0303 health sciences Cultural Characteristics Models Statistical Loneliness 05 social sciences Assortative mating Twin study Genetic architecture Phenotype Trait Female medicine.symptom Psychology Extended twin design |
| Zdroj: | Distel, M A, Rebollo Mesa, I, Abdellaoui, A, Derom, C A, Willemsen, G, Cacioppo, J T & Boomsma, D I 2010, ' Familial Resemblance for Loneliness ', Behavior Genetics, vol. 40, no. 4, pp. 480-494 . https://doi.org/10.1007/s10519-010-9341-5 Behavior Genetics, 40(4), 480-494. Springer Behavior Genetics |
| ISSN: | 1573-3297 0001-8244 |
| DOI: | 10.1007/s10519-010-9341-5 |
| Popis: | Social isolation and loneliness in humans have been associated with physical and psychological morbidity, as well as mortality. This study aimed to assess the etiology of individual differences in feelings of loneliness. The genetic architecture of loneliness was explored in an extended twin-family design including 8,683 twins, siblings and parents from 3,911 families. In addition, 917 spouses of twins participated. The presence of assortative mating, genetic non-additivity, vertical cultural transmission, genotype-environment (GE) correlation and interaction was modeled. GE interaction was considered for several demographic characteristics. Results showed non-random mating for loneliness. We confirmed that loneliness is moderately heritable, with a significant contribution of non-additive genetic variation. There were no effects of vertical cultural transmission. With respect to demographic characteristics, results indicated that marriage, having offspring, more years of education, and a higher number of siblings are associated with lower levels of loneliness. Interestingly, these effects tended to be stronger for men than women. There was little evidence of changes in genetic architecture as a function of these characteristics. We conclude that the genetic architecture of loneliness points to non-additive genetic influences, suggesting it may be a trait that was not neutral to selection in our evolutionary past. Sociodemographic factors that influence the prevalence of loneliness do not affect its genetic architecture. © The Author(s) 2010. |
| Databáze: | OpenAIRE |
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