Tick-paralysis toxoid: an effective immunizing agent against the toxin of Ixodes holocyclus
| Autor: | B F Stone, A L Neish |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Clinical Biochemistry
Immunology medicine.disease_cause complex mixtures Microbiology Tick paralysis Dogs Ticks medicine Paralysis Animals Dog Diseases Arthropod Venoms biology Toxin business.industry Vaccination Toxoid Cell Biology General Medicine Tick Toxicoses biology.organism_classification medicine.disease Virology Ixodes holocyclus Tick Paralysis Humoral immunity Ixodes Rabbits Antitoxin medicine.symptom business |
| Zdroj: | The Australian journal of experimental biology and medical science. 62 |
| ISSN: | 0004-945X |
| Popis: | Glutaraldehyde treatment of the toxin of the Australian paralysis tick Ixodes holocyclus produced a potent, immunogenic toxoid. Three subcutaneous injections (2 to 4 weeks apart) into rabbits produced very high antitoxin titres in their serum, although circulating antitoxin titres declined in the absence of stimulation. Twenty weeks later, immunized rabbits were unaffected by lethal doses of toxin injected subcutaneously. |
| Databáze: | OpenAIRE |
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