When Zoster Virus Hides a Primary Brain Lymphoma
| Autor: | João Miguel Freitas, Maria da Luz Brazão, R F Nascimento |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Madeira Island Nausea lcsh:Medicine lymphoma Zoster virus Ptosis Biopsy Internal Medicine Medicine central nervous system Immunocompetent lymphoma Anisocoria medicine.diagnostic_test business.industry lcsh:R Articles medicine.disease Dermatology Occult Lymphoma Herpes Zoster Ophthalmicus Vomiting Immunocompetent medicine.symptom business |
| Zdroj: | European Journal of Case Reports in Internal Medicine Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP European Journal of Case Reports in Internal Medicine (2019) |
| Popis: | To describe an unusual presentation of a primary lymphoma of the central nervous system in a patient who, four months prior to admission, was diagnosed with herpes zoster ophthalmicus (HZO). Case description: A 68-year-old man, with a history of HZO, was admitted to the emergency department with nausea and vomiting that had persisted over the previous two weeks. Neurological evaluation showed right ptosis, divergent strabismus and anisocoria. Blood tests showed high c-reactive protein, while serology was negative for human immunodeficiency virus. A brain CT scan revealed three round lesions, slightly hyperdense, periventricular in the occipital and frontal regions, which biopsy revealed to be a diffuse large B-cell lymphoma. The patient started chemotherapy but progression to death was inevitable. Conclusion: The authors describe an unusual presentation of primary lymphoma of the central nervous system and urge physicians to be aware of this presentation in order to avoid misdiagnosis. CASE DESCRIPTION A 68-year-old Caucasian male was asymptomatic until two weeks before admission to the emergency department, when he developed nausea and vomiting, which persisted despite antiemetic medication. Other than a diagnosis of right-sided herpes zoster ophthalmicus (HZO), four months before admission, and type 2 diabetes, his past medical history was unremarkable. General examination on admission was normal but neurological examination revealed right ptosis, divergent strabismus and anisocoria. Blood tests revealed normocytic normochromia anaemia with Hb 10.2, VGM 86 fl, leucocytes 5,100×109/l, thrombocytopenia with a platelet count of 91,000×109/l and a C-reactive protein level of 61.5 mg/l (normal |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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