Bright light does not alter muscarinic receptor binding parameters
| Autor: | Ewa Malatynska, Monique L. Giroux, Steven C. Dilsaver |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Male
medicine.medical_specialty Light Clinical Biochemistry Spontaneous recovery Central nervous system Hypothalamus Striatum Toxicology Biochemistry Behavioral Neuroscience Internal medicine Muscarinic acetylcholine receptor Muscarinic Receptor Binding medicine Animals Lighting Biological Psychiatry Pharmacology Mood Disorders Rats Inbred Strains Receptors Muscarinic Corpus Striatum Pathophysiology Rats medicine.anatomical_structure Endocrinology Seasons Psychology Acetylcholine medicine.drug |
| Zdroj: | Pharmacology Biochemistry and Behavior. 38:695-697 |
| ISSN: | 0091-3057 |
| DOI: | 10.1016/0091-3057(91)90038-4 |
| Popis: | Seasonal Affective Disorders (SADs) are disorders of mood characterized by recurrent episodes of illness with a fixed relationship to season. Winter depression is characterized by recurrent onset of depresion in the fall or winter followed by spontaneous recovery in the spring. This syndrome is responsive to treatment with bright light. The pathophysiology of depressive disorders may involve central muscarinic mechanisms. This possibility led to a series of physiological studies. The authors now report that contrary to expectation, treatment with bright light did not decrease the density of muscarinic receptors in either the hypothalamus or striatum. |
| Databáze: | OpenAIRE |
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