Neuro-Behçet’s disease presenting with tumour-like lesions and responding to rituximab
| Autor: | K Chung, Douglas White, J Jade, M Arendse, Z Hussain |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
medicine.medical_specialty 03 medical and health sciences 0302 clinical medicine Prednisone Physiology (medical) Biopsy medicine Humans Papilledema Cyclophosphamide 030203 arthritis & rheumatology medicine.diagnostic_test business.industry Behcet Syndrome Brain General Medicine Mycophenolic Acid medicine.disease Magnetic Resonance Imaging Infliximab Surgery Hydrocephalus Treatment Outcome Neurology Drug Therapy Combination Female Rituximab Neurology (clinical) Neuro-Behçet's disease medicine.symptom business Vasculitis Immunosuppressive Agents 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Journal of Clinical Neuroscience. 32:139-141 |
| ISSN: | 0967-5868 |
| DOI: | 10.1016/j.jocn.2016.03.020 |
| Popis: | We describe a patient with neuro-Behçets disease (NBD) that presented with symptoms of raised intracranial pressure including papilloedema. MRI revealed tumour-like lesions which, on biopsy, confirmed an active vasculitis. Treatment was commenced with prednisone and cyclophosphamide which proved unsuccessful with enlargement of the cerebral mass lesions. Infliximab and mycophenolate were trialled also without benefit. The patient required ventriculoperitoneal shunts to relieve the symptoms of hydrocephalus. Rituximab was then commenced with significant symptomatic and imaging improvement. The case is unique, in our experience, in the need for shunting to relieve the symptoms of hydrocephalus related to vasculitis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect