Chromosomal Localization of the Major Histocompatibility Complex in Cattle and River Buffalo by Fluorescent in Situ Hybridization
| Autor: | James E. Womack, Daniel S. Gallagher, Lino Ferrara, Leopoldo Iannuzzi, G.P. Di Meo, Loren C. Skow |
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| Rok vydání: | 2004 |
| Předmět: |
Genetics
Buffaloes biology DNA–DNA hybridization Chromosome Mapping Chromosome General Medicine In situ hybridization Major histocompatibility complex Homology (biology) Chromosome Banding Major Histocompatibility Complex Antigen Gene mapping biology.protein Animals Cattle Gene Cells Cultured In Situ Hybridization Fluorescence |
| Zdroj: | Hereditas. 118:187-190 |
| ISSN: | 0018-0661 |
| Popis: | The major histocompatibility complex (MHC) in humans is a polymorphic assemblage of over 70 genes which play key roles in the regulation of the immune response (TROWSDALE et al. 1991). The bovine MHC (bovine lymphocyte antigen, BoLA) was assigned to a rather broad region of cattle chromosome 23 (ql3-23) by sequential Q-banding and isotopic in situ hybridization (FRIES et al. 1986; HEDIGER et al. 1991). In the present study, we use sequential RBA-banding and fluorescent in situ hybridization |
| Databáze: | OpenAIRE |
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