Hematocrit and mean arterial blood pressure in pre- and postmenopause women
| Autor: | Miguel A Salazar Vázquez, Marcos Intaglietta, Pedro Cabrales, Bengt Fagrell, Ulf de Faire, Beatriz Y. Salazar Vázquez |
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| Předmět: |
medicine.medical_specialty
Endothelium hematocrit Endocrinology Diabetes and Metabolism Blood viscosity menopause Vasodilation 030204 cardiovascular system & hematology Hematocrit endothelial dysfunction 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases Internal medicine medicine Humans Pharmacology (medical) 030212 general & internal medicine Endothelial dysfunction Mexico Original Research Sweden medicine.diagnostic_test business.industry Public Health Environmental and Occupational Health blood pressure Hematology General Medicine Blood Viscosity medicine.disease Vascular Health and Risk Management 3. Good health Surgery Postmenopause Menopause medicine.anatomical_structure Blood pressure Premenopause Cardiology Female Cardiology and Cardiovascular Medicine Large group business |
| Zdroj: | Europe PubMed Central Vascular Health and Risk Management Scopus-Elsevier |
| Popis: | Beatriz Y Salazar Vázquez1,2, Miguel A Salazar Vázquez3,4, Marcos Intaglietta2, Ulf de Faire5, Bengt Fagrell6, Pedro Cabrales21Facultad de Medicina, 3Department of Physical Chemistry, Universidad Juárez del estado de Durango, Durango, México; 2Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA; 4Department of Pediatrics, Instituto Mexicano del Seguro Social, Durango, México; 5Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Department of Cardiology, Karolinska Institutet, Solna, Stockholm, Sweden; 6Department of Medicine, Karolinska Institutet at Karolinska Hospital, Solna, Stockholm, SwedenAbstract: The relationship between mean arterial blood pressure (MAP) and hematocrit (Hct) was studied in pre- and postmenopause women in the city of Durango, Mexico. Premenopause women show a negative trend between parameters that is not statistically significant. MAP and Hct are directly related in postmenopause women (p < 0.01). It is proposed that that this MAP/Hct relationship is in part due to differences in endothelial function where menopause decreases the capacity of the endothelium to respond to increased blood viscosity and shears stress, leading to the increased production of vasodilator mediators to compensate for changes in blood viscosity due to changes in Hct. Comparison with a large group of postmenopause women in the city of Stockholm showed identical trends.Keywords: menopause, endothelial dysfunction, blood viscosity, blood pressure, hematocrit |
| Databáze: | OpenAIRE |
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