Cryopreserved Ultra-Thick Human Amniotic Membrane for Conjunctival Surface Reconstruction After Excision of Conjunctival Tumors
| Autor: | Hakan Demirci, Thais Shiota Tanaka |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Conjunctival Neoplasm Adult Male medicine.medical_specialty Adolescent medicine.medical_treatment Visual Acuity Conjunctival Neoplasms Ophthalmologic Surgical Procedures Cryopreservation 03 medical and health sciences 0302 clinical medicine Glaucoma surgery medicine Humans Amnion Child Aged Retrospective Studies Aged 80 and over business.industry Suture Techniques Middle Aged Plastic Surgery Procedures Surgery Ophthalmology 030104 developmental biology medicine.anatomical_structure 030221 ophthalmology & optometry Female business |
| Zdroj: | Cornea. 35(4) |
| ISSN: | 1536-4798 |
| Popis: | Cryopreserved ultra-thick human amniotic membrane (AM) is used for glaucoma surgery. We evaluated the use of cryopreserved ultra-thick human AM for conjunctival surface reconstruction after excision of a conjunctival tumor.We retrospectively reviewed the medical records of 28 patients who underwent conjunctival surface reconstruction with cryopreserved ultra-thick human AM after excision of the tumor. The AM was secured to the surrounding conjunctiva and underlying sclera with interrupted 8-0 Vicryl sutures. Clinical data regarding demographics, diagnosis, size and location of conjunctival tumors, patient outcome, and complications were gathered.Of 28 patients, 6 (21.4%) had malignant melanoma, 4 (14.3%) had squamous cell carcinoma, 6 (21.4%) had conjunctival intraepithelial neoplasia, 1 (3.6%) had sebaceous carcinoma, 1 (3.6%) had mucoepidermoid carcinoma, 1 (3.6%) had conjunctival intraepithelial dysplasia, 5 (17.9%) had pterygium, 2 (7.1%) had compound nevus, 1 (3.6%) had a large epithelial inclusion cyst, and 1 (3.6%) patient had a granuloma. The mean area of graft size was 156 ± 120 mm2. Postoperatively, the graft was well tolerated with no failure, discomfort, or dehiscence. During the 17-month mean follow-up, symblepharon, which was clinically nonsignificant, developed in 3 (11%) patients and partial stem cell deficiency was noted in 5 (18%) patients.Cryopreserved ultra-thick human AM is a well-tolerated, effective graft material that is easy to handle. It is a viable alternative for conjunctival surface reconstruction after excision of a conjunctival tumor. |
| Databáze: | OpenAIRE |
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