Benchmarks and Geographic Differences in Gallbladder Cancer Surgery: An International Multicenter Study

Autor:	Eduardo A. Vega, Timothy E. Newhook, Sebastian Mellado, Andrea Ruzzenente, Masayuki Okuno, Mario De Bellis, Elena Panettieri, M. Usman Ahmad, Ignacio Merlo, Jesus Rojas, Agostino M. De Rose, Hiroto Nishino, Andrew J. Sinnamon, Matteo Donadon, Marit S. Hauger, Oscar A. Guevara, Cesar Munoz, Jason W. Denbo, Yun Shin Chun, Hop S. Tran Cao, Rodrigo Sanchez Claria, Ching-Wei D. Tzeng, Xabier De Aretxabala, Marcelo Vivanco, Kristoffer W. Brudvik, Satoru Seo, Juan Pekolj, George A. Poultsides, Guido Torzilli, Felice Giuliante, Daniel A. Anaya, Alfredo Guglielmi, Eduardo Vinuela, Jean-Nicolas Vauthey
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	= 22% and rate of grade > GBC surgical approaches R1 margin rate < BackgroundHigh-quality surgery plays a central role in the delivery of excellent oncologic care. Benchmark values indicate the best achievable results. We aimed to define benchmark values for gallbladder cancer (GBC) surgery across an international population.Patients and MethodsThis study included consecutive patients with GBC who underwent curative-intent surgery during 2000-2021 at 13 centers across seven countries and four continents. Patients operated on at high-volume centers without the need for vascular and/or bile duct reconstruction and without significant comorbidities were chosen as the benchmark group.ResultsOf 906 patients who underwent curative-intent GBC surgery during the study period 245 (27%) were included in the benchmark group. These were predominantly women (n = 174 71%) and had a median age of 64 years (interquartile range 57-70 years). In the benchmark group 50 patients (20%) experienced complications within 90 days after surgery with 20 patients (8%) developing major complications (Clavien-Dindo grade >= IIIa). Median length of postoperative hospital stay was 6 days (interquartile range 4-8 days). Benchmark values included >= 4 lymph nodes retrieved estimated intraoperative blood loss <= 350 mL perioperative blood transfusion rate <= 13% operative time <= 332 min length of hospital stay <= 8 days R1 margin rate <= 7% complication rate <= 22% and rate of grade >= IIIa complications <= 11%.ConclusionsSurgery for GBC remains associated with significant morbidity. The availability of benchmark values may facilitate comparisons in future analyses among GBC patients GBC surgical approaches and centers performing GBC surgery with 20 patients (8%) developing major complications (Clavien-Dindo grade > 50 patients (20%) experienced complications within 90 days after surgery = IIIa complications < = IIIa). Median length of postoperative hospital stay was 6 days (interquartile range 4-8 days). Benchmark values included > = 11%.ConclusionsSurgery for GBC remains associated with significant morbidity. The availability of benchmark values may facilitate comparisons in future analyses among GBC patients perioperative blood transfusion rate < across seven countries and four continents. Patients operated on at high-volume centers without the need for vascular and/or bile duct reconstruction and without significant comorbidities were chosen as the benchmark group.ResultsOf 906 patients who underwent curative-intent GBC surgery during the study period = 332 min and centers performing GBC surgery = 8 days complication rate < = 13% 245 (27%) were included in the benchmark group. These were predominantly women (n = 174 Oncology BackgroundHigh-quality surgery plays a central role in the delivery of excellent oncologic care. Benchmark values indicate the best achievable results. We aimed to define benchmark values for gallbladder cancer (GBC) surgery across an international population.Patients and MethodsThis study included consecutive patients with GBC who underwent curative-intent surgery during 2000-2021 at 13 centers 71%) and had a median age of 64 years (interquartile range 57-70 years). In the benchmark group estimated intraoperative blood loss < = 7% = 350 mL operative time < Surgery = 4 lymph nodes retrieved length of hospital stay <
Databáze:	OpenAIRE
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