Influence of transjugular intrahepatic portosystemic shunts (TIPS) on tissue oxygenation in patients with cirrhosis
| Autor: | Dominique Valla, Annie Elman, Florence Vachiery, Philippe Sogni, Didier Lebrec, Adrian Gadano, Richard Moreau, C. Denié |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Liver Cirrhosis Male medicine.medical_specialty Cirrhosis Gastroenterology Hypoxemia Oxygen Consumption Refractory Internal medicine Ascites medicine Paracentesis Humans Prospective Studies Prospective cohort study Hepatology medicine.diagnostic_test business.industry Hemodynamics Oxygenation Middle Aged medicine.disease Oxygen Respiratory alkalosis Female medicine.symptom Portasystemic Shunt Transjugular Intrahepatic business |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0106-9543 |
| Popis: | Aims/Backgrounds, The aim of this prospective study was to evaluate the influence of transjugular portosystemic intrahepatic shunts (TIPS) on tissue oxygenation in patients with cirrhosis and refractory ascites. Methods: Five shunted patients were included in the study. The blood and tissue oxygenation values were analyzed 12 days and 4 months after TIPS procedure. The results were compared with those observed in patients treated by paracentesis. Results: Unlike patients treated by paracentesis, PaO 2 values remained unchanged throughout follow-up in shunted patients. After the TIPS procedure, there was a transient increase in systemic O 2 transport and O 2 uptake and a transient decrease in O 2 saturation of hepatic oxyhemoglobin. After 4 months, TIPS resulted in an increase in PCO 2 values and bicarbonate concentrations. Conclusions: The TIPS procedure seems to prevent the decrease in PaO 2 observed in patients treated by paracentesis and may improve the respiratory alkalosis of cirrhosis. |
| Databáze: | OpenAIRE |
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