Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts e Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring

Autor: Henner Hollert, Adam Jonáš, Magnus Breitholtz, Pascal Pandard, Tobias Schulze, Nick Zwart, Sergio Jarque, Carole Chalon, Steffen Keiter, Werner Brack, Andrea Schifferli, Carolina Di Paolo, Emmanuelle Maillot-Marechal, Thomas-Benjamin Seiler, Kerstin Bluhm, Richard Ottermanns, Beate I. Escher, Valeria Dulio, Sebastian Buchinger, Yves Marneffe, Ron van der Oost, Radka Zounková, Selim Ait-Aissa, Xavier Cousin, Janet Y. M. Tang, Klára Hilscherová, Etiënne L.M. Vermeirssen, Mai Thao Nguyen, Timo Hamers, Sven Seidensticker, Mario Carere
Přispěvatelé: Chemistry and Biology, Amsterdam Global Change Institute, Institute for Environmental Research, Rheinisch-Westfälische Technische Hochschule Aachen (RWTH), Man-Technology-Environment Research Centre, School of Science and Technology, Örebro University, Institut National de l'Environnement Industriel et des Risques (INERIS), Helmholtz Zentrum für Umweltforschung = Helmholtz Centre for Environmental Research (UFZ), Department of Applied Environmental Science [Stockholm] (ITM), Stockholm University, Department Biochemistry and Ecotoxicology, Federal Institute of Hydrology, Italian Institute of Health, Scientific Institute of Public Service (ISSeP), Laboratoire de Physiologie et Génomique des Poissons (LPGP), Institut National de la Recherche Agronomique (INRA)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Laboratoire d'Ecotoxicologie, Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER), National Research Centre for Environmental Toxicology, University of Southern Queensland (USQ), Center for Applied Geosciences [Tübingen] (ZAG), University of Tübingen, Institute for Environmental Studies, University of Amsterdam [Amsterdam] (UvA), Research Centre for Toxic Compounds in the Environment [Brno] (RECETOX / MUNI), Faculty of Science [Brno] (SCI / MUNI), Masaryk University [Brno] (MUNI)-Masaryk University [Brno] (MUNI), Waterproef Laboratory, Swiss Federal Insitute of Aquatic Science and Technology [Dübendorf] (EAWAG), Division of Technology Research & Engineering, Waternet Institute for the Urban Water Cycle, Institute for Environmental Studies -IVM, This project was developed by the Working Group 2 Bioassays and biomarkers in water quality monitoring of the NORMAN Association ( http://www.norman-network.net ). It was funded and supported by the European Marie Curie Initial Training Network EDA-EMERGE (grant agreement no. 290100, Helmholtz Centre for Environmental Research (UFZ), University of Queensland (UQ), Research Centre for Toxic Compounds in the Environment, Masaryk University, Swiss Centre for Applied Ecotoxicology Eawag-EPFL
Jazyk: angličtina
Rok vydání: 2016
Předmět:
mechanism-specific toxicity
Bioanalysis
Environmental Engineering
010504 meteorology & atmospheric sciences
triclosan
3-Nitrobenzanthrone
[SDV]Life Sciences [q-bio]
Portable water purification
010501 environmental sciences
01 natural sciences
Mechanism-specific toxicity
Water Purification
chemistry.chemical_compound
Water Quality
acridine
Environmental monitoring
Animals
Bioassay
Acridine
Waste Management and Disposal
0105 earth and related environmental sciences
Water Science and Technology
Civil and Structural Engineering
Pollutant
17 alpha-ethinylestradiol
Organism-level toxicity
17α-ethinylestradiol
Chemistry
Ecological Modeling
Water
Contamination
Pollution
Triclosan
6. Clean water
13. Climate action
Environmental chemistry
3-nitrobenzanthrone
Biological Assay
Water quality
organism-level toxicity
SDG 6 - Clean Water and Sanitation
Water Pollutants
Chemical
Environmental Monitoring
Zdroj: Water Research, 104, 473-484. Elsevier Limited
Di Paolo, C, Ottermanns, R, Keiter, S, Ait-Aissa, S, Bluhm, K, Brack, W, Breitholz, M, Buchinger, S, Carere, M, Chalon, C, Cousin, X, Dulio, V, Escher, B I, Hamers, T, Jarque, S, Jonas, A, Maillot-Marechal, E, Marneffe, Y, Nguyen, M T, Pandard, P, Schifferli, A, Schulze, T, Seidensticker, S, Seiler, T B, Tang, J, van der Oost, R, Vermeirssen, E, Zounková, R, Zwart, N & Hollert, H 2016, ' Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts e Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring ', Water Research, vol. 104, pp. 473-484 . https://doi.org/10.1016/j.watres.2016.08.018
Water Research
Water Research, IWA Publishing, 2016, 104, pp.473-484. ⟨10.1016/j.watres.2016.08.018⟩
Water Research (0043-1354) (Pergamon-elsevier Science Ltd), 2016-11, Vol. 104, P. 473-484
ISSN: 0043-1354
Popis: Bioassays are particularly useful tools to link the chemical and ecological assessments in water quality monitoring. Different methods cover a broad range of toxicity mechanisms in diverse organisms, and account for risks posed by non-target compounds and mixtures. Many tests are already applied in chemical and waste assessments, and stakeholders from the science-police interface have recommended their integration in regulatory water quality monitoring. Still, there is a need to address bioassay suitability to evaluate water samples containing emerging pollutants, which are a current priority in water quality monitoring. The presented interlaboratory study (ILS) verified whether a battery of miniaturized bioassays, conducted in 11 different laboratories following their own protocols, would produce comparable results when applied to evaluate blinded samples consisting of a pristine water extract spiked with four emerging pollutants as single chemicals or mixtures, i.e. triclosan, acridine, 17 alpha-ethinylestradiol (EE2) and 3-nitrobenzanthrone (3-NBA). Assays evaluated effects on aquatic organisms from three different trophic levels (algae, daphnids, zebrafish embryos) and mechanism-specific effects using in vitro estrogenicity (ER-Luc, YES) and mutagenicity (Ames fluctuation) assays. The test battery presented complementary sensitivity and specificity to evaluate the different blinded water extract spikes. Aquatic organisms differed in terms of sensitivity to triclosan (algae > daphnids > fish) and acridine (fish > daphnids > algae) spikes, confirming the complementary role of the three taxa for water quality assessment. Estrogenicity and mutagenicity assays identified with high precision the respective mechanism-specific effects of spikes even when non-specific toxicity occurred in mixture. For estrogenicity, although differences were observed between assays and models, EE2 spike relative induction EC50 values were comparable to the literature, and E2/EE2 equivalency factors reliably reflected the sample content. In the Ames, strong revertant induction occurred following 3-NBA spike incubation with the TA98 strain, which was of lower magnitude after metabolic transformation and when compared to TA100. Differences in experimental protocols, model organisms, and data analysis can be sources of variation, indicating that respective harmonized standard procedures should be followed when implementing bioassays in water monitoring. Together with other ongoing activities for the validation of a basic bioassay battery, the present study is an important step towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring. (C) 2016 Elsevier Ltd. All rights reserved.
Databáze: OpenAIRE
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