Neural pathways of maternal responding: systematic review and meta-analysis
| Autor: | Josie Austin, Ipshita Mukherjee, Richard Drake, Ian Ellison-Wright, Alya Elmadih, Kathryn M. Abel, Rebecca Elliott, Sarika Paul, Ming Wai Wan, Darragh Downey, Lisa Heaney, Steve R. Williams |
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| Rok vydání: | 2018 |
| Předmět: |
Visual perception
Maternal sensitivity Review Article Oxytocin Amygdala 03 medical and health sciences 0302 clinical medicine Gyrus Neural Pathways medicine Humans Maternal Behavior medicine.diagnostic_test business.industry fMRI Brain Infant Obstetrics and Gynecology Mother-infant Magnetic Resonance Imaging Mother-Child Relations 030227 psychiatry Functional imaging Psychiatry and Mental health medicine.anatomical_structure Systematic review Meta-analysis Female business Functional magnetic resonance imaging Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Paul, S, Austin, J, Elliott, R, Ellison-Wright, I, Wan, M W, Drake, R, Downey, D, Elmadih, A, Mukherjee, I, Heaney, L, Williams, S & Abel, K M 2018, ' Neural pathways of maternal responding : systematic review and meta-analysis ', Archives of Women's Mental Health . https://doi.org/10.1007/s00737-018-0878-2 Archives of Women's Mental Health |
| ISSN: | 1435-1102 1434-1816 |
| Popis: | Functional magnetic resonance imaging (fMRI) has increasingly been employed to establish whether there is a specific brain neural network dedicated to maternal responsiveness. We undertook systematic review and meta-analysis of all studies in which healthy new mothers were exposed to visual stimuli of own versus other infants to determine the quality of evidence for a dedicated maternal neural network. Systematic literature review revealed a pattern of specific neural responses commonly induced by visual infant paradigms. Brain areas consistently reported as activated in mothers in response to own versus unknown infant included the left thalamus, bilateral pre-central gyrus, left limbic lobe, uncus, amygdala and left caudate. These regions are implicated in reward, attention, emotion processing and other core social cognitive skills. Meta-analysis, however, revealed a more limited subset of brain areas activated in mothers specifically in response to their own versus unknown infant and suggested considerable inter-study variability. Further work is needed if functional imaging is to become an objective tool for the assessment of neural pathways associated with distinct patterns of maternal care behaviour. Such a tool would be invaluable in developing biomarkers of neural activity associated with healthy maternal care and for monitoring treatment/intervention effects of costly parenting interventions. Electronic supplementary material The online version of this article (10.1007/s00737-018-0878-2) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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