Low skeletal muscle mass is associated with increased hospital expenditure in patients undergoing cancer surgery of the alimentary tract
| Autor: | Jan N. M. IJzermans, Stefan Buettner, Marcia P. Gaspersz, Jeroen L.A. van Vugt, Ron W. F. de Bruin, N. Bossche, Stef Levolger, Cornelis Verhoef, Casper H. C. van Eijck, Mustafa Suker, Bas Groot Koerkamp, Robert R. J. Coebergh van den Braak |
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| Přispěvatelé: | Surgery, Erasmus MC other |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Colorectal cancer Cancer Treatment lcsh:Medicine Digestive System Neoplasms Cholangiocarcinoma 0302 clinical medicine Surgical oncology Adenocarcinomas Periampullary cancer Medicine and Health Sciences 030212 general & internal medicine Hospital Costs lcsh:Science Wasting Musculoskeletal System Multidisciplinary Muscles Liver Diseases Organ Size Middle Aged people.cause_of_death Hospitals medicine.anatomical_structure Surgical Oncology Treatment Outcome Oncology 030220 oncology & carcinogenesis Hepatocellular carcinoma Female medicine.symptom Anatomy Research Article Hepatic Resection Clinical Oncology medicine.medical_specialty Surgical and Invasive Medical Procedures Gastroenterology and Hepatology Carcinomas 03 medical and health sciences Digestive System Procedures SDG 3 - Good Health and Well-being Internal medicine Gastrointestinal Tumors medicine Humans Muscle Skeletal Aged Surgical Resection business.industry lcsh:R Cancer Skeletal muscle Biology and Life Sciences Cancers and Neoplasms Hepatocellular Carcinoma medicine.disease Surgery Health Care Skeletal Muscles Health Care Facilities Sarcopenia lcsh:Q Clinical Medicine business people |
| Zdroj: | PLoS ONE, Vol 12, Iss 10, p e0186547 (2017) PLoS ONE PLoS One (online), 12(10):e0186547. Public Library of Science |
| ISSN: | 1932-6203 |
| Popis: | Background: Low skeletal muscle mass is associated with poor postoperative outcomes in cancer patients. Furthermore, it is associated with increased healthcare costs in the United States. We investigated its effect on hospital expenditure in a Western-European healthcare system, with universal access. Methods: Skeletal muscle mass (assessed on CT) and costs were obtained for patients who underwent curative-intent abdominal cancer surgery. Low skeletal muscle mass was defined based on pre-established cut-offs. The relationship between low skeletal muscle mass and hospital costs was assessed using linear regression analysis and Mann-Whitney U-tests. Results: 452 patients were included (median age 65, 61.5% males). Patients underwent surgery for colorectal cancer (38.9%), colorectal liver metastases (27.4%), primary liver tumours (23.2%), and pancreatic/periampullary cancer (10.4%). In total, 45.6% had sarcopenia. Median costs were €2,183 higher in patients with low compared with patients with high skeletal muscle mass (€17,144 versus €14,961; P |
| Databáze: | OpenAIRE |
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