Cytogenetic findings in a large bowel adenocarcinoma
| Autor: | Sotirios A. Raptis, Alex Avgerinos, Anna D. Panani, Angeliki Ferti-Passantonopoulou |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Genetic Markers
Male Cancer Research Pathology medicine.medical_specialty Trisomy Biology Adenocarcinoma Y chromosome Translocation Genetic Genetics medicine Humans Molecular Biology X chromosome Aged Chromosome 7 (human) Chromosome Aberrations medicine.diagnostic_test Rectal Neoplasms Cytogenetics Sigmoidoscopy Karyotype medicine.disease Sigmoid Neoplasms Karyotyping Chromosome Deletion |
| Zdroj: | Cancer genetics and cytogenetics. 21(4) |
| ISSN: | 0165-4608 |
| Popis: | Cytogenetic analysis of a biopsy specimen taken during sigmoidoscopy from an adenocarcinoma of the large bowel revealed a hypodiploid karyotype with numerical and structural abnormalities identified as trisomy 7, t(3;12), t(1;17), interstitial deletion of the long arm of a chromosome #5 and loss of the Y chromosome with double X chromosomes. The possibility of this karyotype being a further evolutionary step in a subgroup of large bowel cancers and the clinical value of the above findings are discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|