Inhibitory effect of proteinase K against dermatophyte biofilms: an alternative for increasing the antifungal effects of terbinafine and griseofulvin

Autor:	Raimunda Sâmia Nogueira Brilhante, Raissa Geovanna Pereira Lopes, Lara de Aguiar, Jonathas Sales de Oliveira, Géssica dos Santos Araújo, Germana Costa Paixão, Waldemiro de Aquino Pereira-Neto, Rosemayre Souza Freire, João Victor Serra Nunes, Renan Pereira de Lima, Flávia Almeida Santos, José Júlio Costa Sidrim, Marcos Fábio Gadelha Rocha
Rok vydání:	2022
Předmět:	Antifungal Agents Arthrodermataceae Biofilms Microbial Sensitivity Tests Aquatic Science Endopeptidase K Applied Microbiology and Biotechnology Terbinafine Griseofulvin Water Science and Technology
Zdroj:	Biofouling. 38(3)
ISSN:	1029-2454
Popis:	This study aimed to evaluate the effect of proteinase K on mature biofilms of dermatophytes, by assays of metabolic activity and biomass. In addition, the proteinase K-terbinafine and proteinase K-griseofulvin interactions against these biofilms were investigated by the checkerboard assay and scanning electron and confocal microscopy. The biofilms exposed to 32 µg ml
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10381923e8a1a6cc6140132f308119dc https://pubmed.ncbi.nlm.nih.gov/35450473 Zobrazit plný text záznamu