Two-Phase Contrast Injection Protocol for Pediatric Cardiac Computed Tomography in Children with Congenital Heart Disease
| Autor: | Hikaru Nishiyama, Akira Kurata, Ryo Tashiro, Teruhito Kido, Takashi Higaki, Naoki Fukuyama, Teruhito Mochizuki, Naoto Kawaguchi, Yuki Tanabe, Takahiro Yokoi, Toshihide Itoh, Masao Miyagawa |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Heart Defects
Congenital Male medicine.medical_specialty Vena Cava Superior Heart Ventricles Contrast Media Aorta Thoracic Vena Cava Inferior Pulmonary Artery 030204 cardiovascular system & hematology Inferior vena cava 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Interquartile range Superior vena cava medicine.artery Hounsfield scale medicine Humans Heart Atria Child Retrospective Studies business.industry Infant Newborn Infant Cardiac surgery medicine.anatomical_structure medicine.vein Ventricle Child Preschool Descending aorta Injections Intravenous Pediatrics Perinatology and Child Health Pulmonary artery cardiovascular system Female Tomography X-Ray Computed Cardiology and Cardiovascular Medicine Nuclear medicine business |
| Zdroj: | Pediatric Cardiology. 39:518-525 |
| ISSN: | 1432-1971 0172-0643 |
| Popis: | To assess a two-phase contrast injection protocol for contrast enhancement during cardiac computed tomography (CT) in children with congenital heart disease. Forty-three children (20 boys, 23 girls) of median age 13 months (range 3 days-8.3 years) and weighing ≤ 20 kg who underwent cardiac CT using a two-phase contrast injection protocol at our institution were retrospectively identified. High-pitch spiral third-generation dual-source cardiac CT (tube voltage 70 kV) was performed with a fixed delay of 60 s after contrast injection in the order of 10 mgI/kg/s (30 s), 15 mgI/kg/s (20 s), and a saline chaser (10 s). Attenuation in the inferior vena cava (IVC), superior vena cava (SVC), right atrium (RA), right ventricle (RV), pulmonary artery (PA), left atrium (LA), left ventricle (LV), and descending aorta (AO) was compared using the Steel-Dwass and Fisher's exact tests. The median (interquartile range) attenuation in the IVC, SVC, RA, RV, PA, LA, LV, and AO was 285 (264-347) Hounsfield units (HU), 416 (370-445) HU, 368 (320-388) HU, 373 (322-417) HU, 397 (330-432) HU, 425 (373-469) HU, 435 (385-468) HU, and 437 (392-491) HU, respectively (p 0.05, IVC vs. the other anatomic sites). There was no significant difference in diagnostic success rate for attenuation 250 HU between the IVC (41 children, 95.3%) and the other sites (43 children, 100%). A two-phase contrast injection protocol is useful for effective contrast enhancement in pediatric cardiac CT. |
| Databáze: | OpenAIRE |
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