ASPECTS is a predictor of favorable CT perfusion in acute ischemic stroke
| Autor: | Archana Hinduja, Shadi Yaghi, Nicholas Bianchi, Adewumi Amole |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Perfusion scanning Risk Assessment Sensitivity and Specificity Severity of Illness Index Brain Ischemia medicine.artery Internal medicine medicine Prevalence Humans heterocyclic compounds Radiology Nuclear Medicine and imaging Endovascular treatment Head and neck Acute ischemic stroke Stroke Aged Aged 80 and over Arkansas Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Reproducibility of Results Middle Aged medicine.disease Surgery Cerebral Angiography Multivariate logistic regression model Middle cerebral artery Angiography Cardiology Radiographic Image Interpretation Computer-Assisted Female Neurology (clinical) business Tomography X-Ray Computed |
| Zdroj: | Journal of neuroradiology = Journal de neuroradiologie. 41(3) |
| ISSN: | 0150-9861 |
| Popis: | Summary Background and purpose Computed tomography perfusion (CTP) is used by some stroke centers to stratify stroke patients who may potentially benefit from endovascular treatment. Our aim is to identify predictors of a favorable CTP in acute ischemic stroke patients evaluated within 8 h from symptoms onset for possible endovascular treatment. Materials and methods We reviewed records of patients who had CTP studies between August 2010 and September 2012. We included all patients with anterior circulation strokes with evidence of large vessel disease. All patients had CT head and CT angiography head and neck as part of our protocol. Favorable CTP was defined as core infarct size less than one third the middle cerebral artery distribution and penumbra > 20% of infarct size. The patients were divided into two groups based on favorable CTP or not. Baseline characteristics, time parameters, laboratory data and radiological data were compared between both groups. For statistical analysis, we used independent and Fisher's exact tests and a multivariate logistic regression model. Results During this period, 60 patients met the inclusion criteria. Patients with favorable CTP were likely to be ≥ 80 years (33% vs 9%, P = 0.026), have Alberta Stroke Program early CT score (ASPECTS) > 7 (81% v. 21%, P ≤ 0.001) and lower mean time from symptom onset to CTP (234 ± 91 vs 305 ± 122, P = 0.015). On regression analysis, ASPECTS was the only independent predictor of a favorable CTP (OR = 16.2, CI: 4.3–62.2, P Conclusion ASPECT score may be used as a tool to predict a favorable CTP. Larger studies are needed to confirm our findings. |
| Databáze: | OpenAIRE |
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