Oligohydramnios and growth restriction do not portend worse prognosis in gastroschisis pregnancies
| Autor: | Sina Haeri, Robert C. Johnston |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Intrauterine growth restriction Oligohydramnios Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy Risk Factors Prenatal Diagnosis 030225 pediatrics medicine Birth Weight Humans Retrospective Studies Gastroschisis Analysis of Variance Fetal Growth Retardation 030219 obstetrics & reproductive medicine Neonatal sepsis business.industry Obstetrics Abdominal wall defect Infant Newborn Pregnancy Outcome Obstetrics and Gynecology Retrospective cohort study Prognosis medicine.disease Infant Small for Gestational Age Pediatrics Perinatology and Child Health Female Apgar score Neonatal Sepsis business |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 29:4055-4058 |
| ISSN: | 1476-4954 1476-7058 |
| DOI: | 10.3109/14767058.2016.1154939 |
| Popis: | Gastroschisis is a common abdominal wall defect. While most neonates have an excellent prognosis, complications do occur. Several risk factors for adverse neonatal outcomes have been identified, however, the impact of intrauterine growth restriction (IUGR) and oligohydramnios on neonatal morbidity and mortality has not been fully elucidated.In this retrospective cohort study of pregnancies complicated by gastroschisis at two tertiary-care centers during an eight-year period, maternal, fetal and neonatal data were analyzed to estimate the impact of IUGR and oligohydramnios upon neonatal outcomes. Adverse outcomes were defined as five-minute Apgar score7, umbilical cord pH7.12, neonatal sepsis, prolonged ventilator support, prolonged total parenteral nutrition, extended NICU stay, death and a composite of the above.Among the 179 cases of gastroschisis, there were no differences in maternal demographics between cases with and without IUGR or oligohydramnios. Fetuses with oligohydramnios demonstrated a trend toward lower birthweight (p = 0.06). Small for gestational age infants showed a trend toward prolonged ventilator support (p = 0.06). Oligohydramnios and IUGR were otherwise not associated with adverse neonatal outcomes.While risk factors for adverse neonatal outcomes have been identified in pregnancies complicated by gastroschisis, IUGR and oligohydramnios do not appear to be among them. |
| Databáze: | OpenAIRE |
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