HOMOGENIZATION AND μCT ANALYSIS FOR THE TRABECULAR BONE REMODELLING
| Autor: | Mathias Brieu, Jean-Louis Milan, Jean-François Witz, Claudia Chan Yone, Jean-Marie Rossi, Patrick Chabrand |
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| Přispěvatelé: | Institut des Sciences du Mouvement Etienne Jules Marey (ISM), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2012 |
| Předmět: |
Materials science
Bone density Rehabilitation Biomedical Engineering Biophysics [SPI.MECA.BIOM]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph] Homogenization (chemistry) Bone remodeling Resorption Apposition Trabecular bone Orthopedics and Sports Medicine Bone stiffness ComputingMilieux_MISCELLANEOUS Biomedical engineering |
| Zdroj: | Journal of Biomechanics Journal of Biomechanics, 2012, 45, pp.S532. ⟨10.1016/S0021-9290(12)70533-X⟩ |
| ISSN: | 0021-9290 |
| DOI: | 10.1016/s0021-9290(12)70533-x |
| Popis: | Fractures in trabecular bone are due to degradations: bone density decreases and microarchitecture is altered with respect to aging. Many authors aimed modelling degradation of trabecular bone architecture due to aging or disease ([Adachi, 2001], [Muller, 2005], [Liu, 2008]). The precited models were only based on biological kinetics and parameters: lengths of apposition and resorption phase, depth of resorption lacunae, frequency activation... However, models considered millions of elements and did not integrate mechanical stimulus as a precursor of bone remodelling adaptation. As a result, they have simulated the micro-structure degradation and not the influence of mechanical stimulus on bone stiffness. |
| Databáze: | OpenAIRE |
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