Influence of triamcinolone and somatostatin on morphometric parameters of cultured intestinal mucosa
Autor: | Hans Ditschuneit, G. Grösch, A. Schneider, Eduard F. Stange |
---|---|
Rok vydání: | 1986 |
Předmět: |
medicine.medical_specialty
Triamcinolone acetonide Clinical Biochemistry Crypt Mitosis Ileum Plant Science Biology Organ culture Triamcinolone Organ Culture Techniques Intestinal mucosa Internal medicine medicine Animals Intestinal Mucosa Metaphase Lagomorpha Microvilli Cell growth Cell Biology biology.organism_classification Endocrinology medicine.anatomical_structure Somatostatin Rabbits Biotechnology Developmental Biology medicine.drug |
Zdroj: | In vitro cellulardevelopmental biology : journal of the Tissue Culture Association. 22(11) |
ISSN: | 0883-8364 |
Popis: | Mucosal biopsies from rabbit ileum were organ cultured for 24 h. The influence of triamcinolone and somatostatin on villus height and diameter as well as crypt depth and the number of mitoses was measured at various times during 24 h of culture as indices of cell proliferation and tissue maintenance. It could be shown that triamcinolone reduced cell proliferation slightly but preserved mucosal structure in organ culture. Somatostatin inhibited crypt cell proliferation, without any effect on other morphological parameters. |
Databáze: | OpenAIRE |
Externí odkaz: |