| Autor: |
Metehan Imamoglu, Huseyin Ekici, Firat Okmen, Mete Ergenoglu |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Archives of Gynecology and Obstetrics. 308:111-116 |
| ISSN: |
1432-0711 |
| Popis: |
PurposeCirrhosis is a diffuse pathology characterized by fibrosis of the liver and is the last stage of chronic liver diseases. It is a serious medical condition which seriously impacts reproduction and reproductive life span. MethodsRetrospective chart review of the fetal and maternal results of 20 pregnant women with liver cirrhosis who had undergone antenatal follow-up and delivery at a tertiary center in a 12-year period was performed. ResultsChronic hepatitis B was found to be the leading cause of liver cirrhosis in the study group, with a rate of 25 % (n: 5/20). The average MELD score was calculated as 8.8 ± 3.5. Only three patients developed hepatic decompensation during pregnancy. Fetal demise was observed in 10% of the cases (n: 2/20, MELD scores 8 and 17).ConclusionEven though pregnancy is rarely observed in women with liver cirrhosis, many patients with are able to achieve favorable maternal and fetal results without developing hepatic decompensation with appropriate management and close follow-up. The Model for End-Stage Liver Disease (MELD) score is a clinical tool utilized to estimate the severity and survival for chronic liver disease and was previously found to be associated with unfavorable outcomes in pregnant patients. Our study confirms this finding with the current experience from a tertiary care center. In addition, with the effects of cirrhosis on pregnancy being a concern, the impact of pregnancy on the course of the disease should also be addressed. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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