Plasma carotenoids as biomarkers of intake of fruits and vegetables: ecological-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC)
| Autor: | Miren Dorronsoro, Nadia Slimani, Gabriele Nagel, Egidio Celentano, Guri Skeie, A. Agudo, C. H. van Gils, Heiner Boeing, Eiliv Lund, Ailsa A Welch, Ingegerd Johansson, Timothy J. Key, Sheila Bingham, A. L. Van Kappel, Françoise Clavel-Chapelon, Kim Overvad, Ma Dolores Chirlaque, Antonia Trichopoulou, Pamela Ferrari, Elio Riboli, Marga C. Ocké, Anne Tjønneland, Elizabeth A Spencer, Androniki Naska, A. Olsen, Eva Ardanaz, M. C. Boutron-Ruault, Irene Mattisson, H. B. Bueno-De-Mesquita, Emmanuelle Kesse, E. Wirfält, Domenico Palli, P. H. M. Peeters, J.-P. Steghens, Carmen Martinez-Garcia, J. Linseisen, G Johansson, Wael K. Al-Delaimy, R. Tumino, Carlotta Sacerdote, J. R. Quirós, Sabina Sieri |
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| Přispěvatelé: | University of Groningen |
| Rok vydání: | 2005 |
| Předmět: |
Male
LYCOPENE Medicine (miscellaneous) Antioxidants SERUM Cohort Studies chemistry.chemical_compound Surveys and Questionnaires Vegetables Medicine Longitudinal Studies Prospective Studies Food science Carotenoid chemistry.chemical_classification Nutrition and Dietetics carotenoids food and beverages Middle Aged Lycopene European Prospective Investigation into Cancer and Nutrition Europe Zeaxanthin Calibration Female ecology 24-h dietary recall NUTRIENT INTAKE Diet therapy fruits and vegetables Sensitivity and Specificity Predictive Value of Tests beta-Carotene 24-HOUR DIET RECALL Humans ddc:610 BIOCHEMICAL MARKERS plasma VITAMIN-C business.industry BETA-CAROTENE CONSUMPTION ADULTS FOOD FREQUENCY QUESTIONNAIRES chemistry Fruit Mental Recall Cryptoxanthin business EPIC Body mass index Biomarkers |
| Zdroj: | Al-Delaimy, WK, Slimani, N, Ferrari, P, Spencer, E, Johansson, I, Johansson, G, Matisson, I, Wirfalt, E, Sieri, S, Agudo, A, Celentano, E, Palli, D, Sacerdote, C, Tumin, R, Dorronsoro, M, Ocke, MC, Bueno-De-Mesquita, HB, Overvad, K, Chirlaque, MC, Trichopoulou, A, Naske, A, Tjønnland, A, Olsen, A V, Lund, E, Lund, E, Skeie, G, Ardanaz, E, Kesse, E, Boutron-Ruault, MC, Clavel-Chapelon, F, Bingham, S, Welch, AA, Martinez-Garcia, C, Nagel, G, Linseisen, J, Quiros, JR, Peeters, PH, van Gils, CH, Boeing, H, van Kappel, AL, Stephens, JP & Riboli, E 2005, ' Plasma carotenoids as biomarkers of intake of fruits and vegetables: ecological-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC). ', European Journal of Clinical Nutrition, vol. 59, pp. 1397-408 . European Journal of Clinical Nutrition, 59(12), 1397. Nature Publishing Group European Journal of Clinical Nutrition, 59(12), 1397-1408. Nature Publishing Group Aarhus University |
| ISSN: | 0954-3007 |
| Popis: | Objective: The aim in this study was to assess the association between individual plasma carotenoid levels (alpha-carotene, beta-carotene, lycopene, beta-cryptoxanthin, lutein, zeaxanthin) and fruit and vegetable intakes recorded by a calibrated food questionnaire (FQ) and 24- h dietary recall records (24HDR) in nine different European countries with diverse populations and widely varying intakes of plant foods. Design: A stratified random subsample of 3089 men and women from nine countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC), who had provided blood samples and dietary and other lifestyle information between 1992 and 2000, were included. Results: beta-Cryptoxanthin was most strongly correlated with total fruits (FQ r = 0.52, 24HDR r = 0.39), lycopene with tomato and tomato products (FQ r = 0.38, 24HDR r = 0.25), and alpha-carotene with intake of root vegetables (r = 0.39) and of total carrots (r = 0.38) for FQ only. Based on diet measured by FQ and adjusting for possible confounding by body mass index (BMI), age, gender, smoking status, alcohol intake, and energy intake, the strongest predictors of individual plasma carotenoid levels were fruits (R-partial(2) = 17.2%) for beta-cryptoxanthin, total carrots (R-partial(2) = 13.4%) and root vegetables (R-partial(2) = 13.3%) for alpha-carotene, and tomato products (R-partial(2) = 13.8%) for lycopene. For 24HDR, the highest R-partial(2) was for fruits in relation to beta-cryptoxanthin (7.9%). Conclusions: Intakes of specific fruits and vegetables as measured by food questionnaires are good predictors of certain individual plasma carotenoid levels in our multicentre European study. At individual subject levels, FQ measurements of fruits, root vegetables and carrots, and tomato products are, respectively, good predictors of beta-cryptoxanthin, alpha-carotene, and lycopene in plasma. |
| Databáze: | OpenAIRE |
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