Determinants of Quality of Life in Marfan Syndrome
| Autor: | Eloisa Arbustini, Francesca Stramesi, Aliria Callegari, Catherine Klersy, Pierluigi Politi, Paolo Fusar-Poli |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male musculoskeletal diseases Marfan syndrome congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Systemic disease Psychometrics Health Behavior Marfan Syndrome Sex Factors Arts and Humanities (miscellaneous) Quality of life Surveys and Questionnaires Adaptation Psychological medicine Humans Karnofsky Performance Status Applied Psychology Demography Depression business.industry Healthy population Psychological distress medicine.disease Connective tissue disease Surgery Psychiatry and Mental health Well-being Quality of Life Female Functional status business Clinical psychology |
| Zdroj: | Psychosomatics. 49:243-248 |
| ISSN: | 0033-3182 |
| Popis: | Background Marfan syndrome (MFS) is a rare, heritable disorder that affects connective tissue. Men and women are equally affected. Clinical manifestations involve multiple sites, especially bones and ligaments and heart and blood vessels. Objective Authors sought to investigate quality of life (QoL) in MFS patients, assessing positive and negative sociodemographic factors and self-perceived well-being and functional status. Method Thirty-six patients affected by MFS were interviewed and were administered the SF–36 psychometric questionnaire. Results Subjects affected by MFS reported an impaired quality of life in the psychological domain but not in the physical domain, as compared with a healthy population. Being male and older was significantly associated with a poorer perceived mental QoL. Conclusion The authors found that MFS negatively influences QoL, increases psychological distress, and may be a possible risk for some psychiatric disorders. |
| Databáze: | OpenAIRE |
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