Vitamin B12 Deficiency and Hemoglobin H Disease Early Misdiagnosed as Thrombotic Thrombocytopenic Purpura: A Series of Unfortunate Events
| Autor: | E. Gigi, Efthymia Vlachaki, Panagiotis Andreadis, Marily Pasakiotou, Stergios Arapoglou, Evaggelia Vetsiou, Stamatia Theodoridou |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Pediatrics
medicine.medical_specialty lcsh:RC633-647.5 business.industry Anemia medicine.medical_treatment Thalassemia Thrombotic thrombocytopenic purpura Case Report lcsh:Diseases of the blood and blood-forming organs General Medicine medicine.disease Intensive care unit law.invention Hemoglobinopathy law hemic and lymphatic diseases medicine business Hemoglobin H Disease Central venous catheter pernicious anemia |
| Zdroj: | Case Reports in Hematology Case Reports in Hematology, Vol 2015 (2015) |
| ISSN: | 2090-6579 2090-6560 |
| DOI: | 10.1155/2015/478151 |
| Popis: | We herein would like to report an interesting case of a patient who presented with anemia and thrombocytopenia combined with high serum Lactic Dehydrogenase where Thrombotic Thrombocytopenic Purpura was originally considered. As indicated a central venous catheter was inserted in his subclavian vein which led to mediastinal hematoma and finally intubation and Intensive Care Unit (ICU) hospitalization. After further examination patient was finally diagnosed with B12 deficiency in a setting of H hemoglobinopathy. There have been previous reports where pernicious anemia was originally diagnosed and treated as Thrombotic Thrombocytopenic Purpura but there has been none to our knowledge that was implicated with hemothorax and ICU hospitalization or correlated with thalassemia and we discuss the significance of accurate diagnosis in order to avoid adverse reactions and therapy implications. |
| Databáze: | OpenAIRE |
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