Impact of COVID-19 pandemic lockdown on narcolepsy type 1 management
| Autor: | Elena Antelmi, Giuseppe Plazzi, Emanuela Postiglione, Anastasia Mangiaruga, Uberto Pagotto, Francesca Ingravallo, Fabio Pizza, Claudia Oriolo, Luca Vignatelli, Monica Moresco, Marco Filardi |
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| Přispěvatelé: | Postiglione E., Pizza F., Ingravallo F., Vignatelli L., Filardi M., Mangiaruga A., Antelmi E., Moresco M., Oriolo C., Pagotto U., Plazzi G., DIP. DI SCIENZE NEUROLOGICHE, DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE, DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE, Da definire, AREA MIN. 06 - Scienze mediche |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Employment Male Pediatrics medicine.medical_specialty Cataplexy Coronavirus disease 2019 (COVID-19) behavioral therapy COVID-19 lockdown narcolepsy type 1 smart working Population Neurosciences. Biological psychiatry. Neuropsychiatry Nocturnal Severity of Illness Index 050105 experimental psychology 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine COVID‐19 Pandemic medicine Paralysis Humans 0501 psychology and cognitive sciences education Pandemics Narcolepsy Original Research education.field_of_study business.industry SARS-CoV-2 05 social sciences Middle Aged medicine.disease Telemedicine Italy Quarantine Female medicine.symptom business Body mass index 030217 neurology & neurosurgery RC321-571 |
| Zdroj: | Brain and Behavior Brain and Behavior, Vol 11, Iss 1, Pp n/a-n/a (2021) |
| ISSN: | 2162-3279 |
| Popis: | Study Objectives Narcolepsy type 1 (NT1) is a chronic rare hypersomnia of central origin requiring a combination of behavioral and pharmacological treatments. During the coronavirus disease 2019 (COVID‐19) pandemic, in Italy the population was forced into a lockdown. With this study, we aimed to describe the lockdown impact on NT1 symptom management, according to different patients' working schedule. Methods In the period between 10 April and 15 May 2020, we performed routine follow‐up visits by telephone (as recommended during the COVID‐19 emergency) to 50 patients >18 years old (40% males) under stable long‐term treatment. We divided patients into three groups: unchanged working schedule, forced working/studying at home, and those who lost their job (“lost occupation”). Current sleep–wake habit and symptom severity were compared with prelockdown assessment (six months before) in the three patient groups. Results At assessment, 20, 22, and eight patients belonged to the unchanged, working/studying at home, and lost occupation groups, respectively. While in the lost occupation group, there were no significant differences compared with prepandemic assessment, the patients with unchanged schedules reported more nocturnal awakenings, and NT1 patients working/studying at home showed an extension of nocturnal sleep time, more frequent daytime napping, improvement of daytime sleepiness, and a significant increase in their body mass index. Sleep‐related paralysis/hallucinations, automatic behaviors, cataplexy, and disturbed nocturnal sleep did not differ. Conclusions Narcolepsy type 1 patients working/studying at home intensified behavioral interventions (increased nocturnal sleep time and daytime napping) and ameliorated daytime sleepiness despite presenting with a slight, but significant, increase of weight. The graphical abstract displays that NT1 patients working/studying at home slept more with improved subjective daytime sleepiness, while both NT1 patients working/studying at home and loosing occupation because of the pandemic significantly increased BMI. |
| Databáze: | OpenAIRE |
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