Prognostic value of heart rate turbulence and its relation to inflammation in patients with unstable angina pectoris
| Autor: | Sergio Valsecchi, Antonio Giuseppe Rebuzzi, Attilio Maseri, Domenico Cianflone, Gregory A. Sgueglia, Gaetano Antonio Lanza, Filippo Crea, Alfonso Sestito, Giulia Angeloni |
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| Přispěvatelé: | Lanza, Ga, Sgueglia, Ga, Angeloni, G, Valsecchi, S, Sestito, A, Rebuzzi, Ag, Crea, F, Maseri, A, Cianflone, Domenico |
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Inflammation Heart rate turbulence Angina Heart Rate Internal medicine Heart rate medicine Humans In patient Angina Unstable Myocardial infarction Aged Unstable angina business.industry Middle Aged Prognosis medicine.disease C-Reactive Protein Circulatory system Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE Cardiology Female medicine.symptom Cardiology and Cardiovascular Medicine business heart rate turbolence |
| Popis: | Heart rate turbulence (HRT) provided insights into cardiac autonomic function and predicted clinical outcome in patients with myocardial infarction. A relation between cardiac autonomic function and inflammation was shown in several clinical settings. To assess the prognostic impact of HRT and its relation with inflammation in patients with unstable angina pectoris (UAP), HRT parameters (turbulence onset [TO] and turbulence slope [TS]) were measured in 331 patients with UAP (age 66.4 +/- 10 years; 231 men) with premature ventricular complexes on electrocardiographic Holter monitoring. Total and cardiac mortality were assessed at the 6-month follow-up. The 6th (-1.52%) and 4th deciles (4.90 ms/RR) were the best prognostic cut-off values for TO and TS, respectively. TS -1.52% were 2.94 (95% CI 1.11 to 7.81, p = 0.03) and 3.33 (95% CI 1.13 to 9.79, p = 0.029), respectively. Patients with TO 4.9 ms/RR showed very low risks of total and cardiac mortality (1.8% and 0.9%, respectively). TS |
| Databáze: | OpenAIRE |
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