Effects of electroconvulsive therapy on cognition and quality of life in schizophrenia

Autor: Xiao Wei, Tan, Kenny Wai Kwong, Lim, Donel, Martin, Phern Chern, Tor
Rok vydání: 2022
Předmět:
Zdroj: Annals of the Academy of Medicine, Singapore. 51:400-408
ISSN: 0304-4602
DOI: 10.47102/annals-acadmedsg.202292
Popis: Introduction: The effects of electroconvulsive therapy (ECT) on quality of life (QoL), and its relationship with symptom and cognitive change remains unclear. We aim to examine the association of QoL changes with psychiatric symptom and cognitive changes among patients with schizophrenia who underwent ECT. Methods: This is a retrospective cohort study of 132 patients who received ECT from July 2017 to December 2019. Sociodemographic and clinical characteristics were obtained from medical records. Changes in QoL, psychiatric symptoms and cognition function were examined after 6 sessions of ECT. Generalised linear regression was used to examine the associations of Brief Psychiatric Rating Scale (BPRS) scores and Montreal Cognitive Assessment (MoCA) scores with QoL as measured by EQ-5D scores. Results: The mean (standard error) improvements after ECT were statistically significant for the assessment scales of EQ-5D utility score: 0.77 (0.02) to 0.89 (0.02), P
Databáze: OpenAIRE