Chromosomal localization of the human and mouse histidine decarboxylase genes by in situ hybridization. Exclusion of the HDC gene from the Prader-Willi syndrome region
| Autor: | Jean Thibault, Marie-Geneviève Mattei, Perrine Malzac, Gilles Bruneau |
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| Přispěvatelé: | Unité de recherche Physiologie de la reproduction des mammifères domestiques, Nouzilly, Institut National de la Recherche Agronomique (INRA), ProdInra, Migration |
| Jazyk: | angličtina |
| Rok vydání: | 1996 |
| Předmět: |
[SDV]Life Sciences [q-bio]
In situ hybridization [INFO] Computer Science [cs] Biology Histidine Decarboxylase LOCALISATION 03 medical and health sciences Chromosome 15 Mice Gene mapping Complementary DNA Genetics Animals Humans [INFO]Computer Science [cs] Gene Genetics (clinical) In Situ Hybridization ComputingMilieux_MISCELLANEOUS 030304 developmental biology Synteny 0303 health sciences 030305 genetics & heredity Chromosome Chromosome Mapping BIOLOGIE MOLECULAIRE Molecular biology Histidine decarboxylase [SDV] Life Sciences [q-bio] SYNDROME DE PRADER-WILLI RAT DNA Probes Prader-Willi Syndrome |
| Zdroj: | Human Genetics Human Genetics, Springer Verlag, 1996, 97, pp.359-361 |
| ISSN: | 0340-6717 1432-1203 |
| Popis: | Using a rat histidine decarboxylase (HDC) cDNA probe, we have mapped the HDC gene by in situ hybridization to the ql5–q2l region of human chromosom e15 and to the E5-G region of murine chromosome 2. These localizations strengthen a syntenic group conserved between human chromosome 15 and mouse chromosome 2. The localization of the HDC gene on the human chromosome 15 map shows that it is not included within the Prader-Willi Syndrome region (PWCR). |
| Databáze: | OpenAIRE |
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