Erythroid cells in suppressing leukemia cell growth
| Autor: | Galina V. Seledtsova, Olga V. Poveschenko, M. A. Fel’de, Vladimir Senyukov, Vladimir A. Kozlov, V. I. Seledtsov, D. M. Samarin |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Cancer Research
Bone Marrow Cells Mice Inbred Strains Biology Inhibitory postsynaptic potential Mice Erythroid Cells hemic and lymphatic diseases medicine Tumor Cells Cultured Animals Leukemia L1210 Erythropoietin Cells Cultured Leukemia Experimental Cell growth Mastocytoma Hematology medicine.disease Lymphoma Leukemia medicine.anatomical_structure Oncology Immunology Cancer research Erythroid cell Bone marrow Cell Division medicine.drug |
| Zdroj: | Leukemialymphoma. 46(9) |
| ISSN: | 1042-8194 |
| Popis: | This paper indicates that murine nucleated erythroid cells (EC) are able to reduce, in a dose-dependent manner, the proliferation of both L1210 lymphoma and P815 mastocytoma cells and that the leukemia cell growth inhibitory activity of unseparated bone marrow (BM) cells may be markedly augmented by their short-term culturing with erythropoietin (Epo). These results raise the intriguing possibility to utilize erythropoesis-stimulating, therapeutic strategies with the purpose of inhibiting leukemia cell growth in the body. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|