Human Cytomegalovirus morphogenesis: an ultrastructural study of the late cytoplasmic phases
| Autor: | E. Govoni, M. P. Landini, B. Severi |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Human cytomegalovirus
viruses Morphogenesis Cytomegalovirus Golgi Apparatus Biology Virus Replication Virus Cell Line symbols.namesake Virology Organelle medicine Humans Cell Membrane Biological Transport General Medicine Golgi apparatus medicine.disease Cell Compartmentation Cell biology Microscopy Electron Cell culture Cytoplasm symbols Ultrastructure |
| Zdroj: | Archives of Virology. 98:51-64 |
| ISSN: | 1432-8798 0304-8608 |
| DOI: | 10.1007/bf01321005 |
| Popis: | The late cytoplasmic phases of human Cytomegalovirus (HCMV) morphogenesis in cultured fibroblasts have been studied by transmission electron microscopy focusing attention on the relationship between the viral particles and host cell organelles. The results obtained largely reflect changes in cells subjected to sublethal injurious stimuli induced by many viruses as well as different noxious agents. A great increase in the number of Golgi apparatuses and lysosomes was observed, both of them interacting with the viral progeny. HCMV seems to acquire its final envelope from Golgi-derived structures and, less frequently, from the plasma membrane. |
| Databáze: | OpenAIRE |
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