Tuberculosis-like lesions arising from the use of Freund's complete adjuvant in an owl monkey (Aotus sp.)
| Autor: | Alfonso Gozalo, J. Roger Broderson, Richard E. Weller, Carlos A. Málaga |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Male
Pathology medicine.medical_specialty Necrosis Tuberculosis medicine.medical_treatment Embolism Freund's Adjuvant Biology parasitic diseases medicine Animals Lung Hematologic Tests General Veterinary Malaria vaccine Histological Techniques Monkey Diseases medicine.disease medicine.anatomical_structure Freund's adjuvant Immunology Aotidae Animal Science and Zoology Lymph Nodes medicine.symptom Adjuvant Malaria |
| Zdroj: | Journal of Medical Primatology. 33:109-112 |
| ISSN: | 1600-0684 0047-2565 |
| DOI: | 10.1111/j.1600-0684.2004.00060.x |
| Popis: | An apparently normal, non-tuberculin-reacting, splenectomized owl monkey presented tuberculosis-like lesions of the lung at necropsy. Histological and bacteriological examination failed to demonstrate the presence of acid-fast organisms. Retrospective inquiry showed the animal had been inoculated using complete Freund's adjuvant during a malaria vaccine trial. Lesions observed were compatible with lipid embolism of the adjuvant in the lungs. |
| Databáze: | OpenAIRE |
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