Dynamic computed tomographic assessment of the mitral annulus in patients with and without mitral prolapse
| Autor: | Ian T. Mark, Roy P. Marcus, Rickey E. Carter, Thomas A. Foley, Asim Rizvi, Eric E. Williamson, Yugene Guo, Emily N. Sheedy, Nikkole M. Weber, Shuai Leng |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Computed Tomography Angiography Mitral prolapse Cardiac-Gated Imaging Techniques 030204 cardiovascular system & hematology Coronary Angiography 030218 nuclear medicine & medical imaging Electrocardiography 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Mitral valve Humans Medicine Mitral valve prolapse Radiology Nuclear Medicine and imaging In patient cardiovascular diseases Mitral annulus Aged Retrospective Studies Computed tomography angiography Observer Variation Mitral Valve Prolapse Cardiac cycle medicine.diagnostic_test business.industry Reproducibility of Results Middle Aged medicine.disease Circumference medicine.anatomical_structure cardiovascular system Mitral Valve Female Cardiology and Cardiovascular Medicine business Nuclear medicine |
| Zdroj: | Journal of Cardiovascular Computed Tomography. 14:502-509 |
| ISSN: | 1934-5925 |
| DOI: | 10.1016/j.jcct.2020.02.005 |
| Popis: | To obtain 3D CT measurements of mitral annulus throughout cardiac cycle using prototype mitral modeling software, assess interobserver agreement, and compare among patients with mitral prolapse (MP) and control group.Pre-procedural imaging is critical for planning of transcatheter mitral valve (MV) replacement. However, there is limited data regarding reliable CT-based measurements to accurately characterize the dynamic geometry of the mitral annulus in patients with MV disease.Patients with MP and control subjects without any MV disease who underwent ECG-gated cardiac CT were retrospectively identified. Multiphasic CT data was loaded into a prototype mitral modeling software. Multiple anatomical parameters in 3D space were recorded throughout the cardiac cycle (0-95%): annular circumference, planar-surface-area (PSA), anterior-posterior (A-P) distance, and anterolateral-posteromedial (AL-PM) distance. Comparisons were made among the two groups, with p 0.05 considered statistically significant. Interobserver agreement was assessed on ten patients using intraclass correlation coefficient (ICC) among 4 experienced readers.A total of 100 subjects were included: 50 with MP and 50 control. Annular dimensions were significantly higher in the MP group than control group, with circumference (144 ± 11 vs. 117±8 mm), PSA (1533 ± 247 vs. 1005 ± 142 mmA significant variation in the mitral annular measures between different cardiac phases and two groups was observed with excellent interobserver agreement. |
| Databáze: | OpenAIRE |
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