Relation of 24-hour urinary caffeine and caffeine metabolite excretions with self-reported consumption of coffee and other caffeinated beverages in the general population

Autor: Fred Paccaud, Pierre-Yves Martin, Idris Guessous, Murielle Bochud, Markus G. Mohaupt, Belen Ponte, Daniel Ackermann, Menno Pruijm, Dusan Petrovic, Bruno Vogt, Chin B. Eap, Nicolas Ansermot, Sandrine Estoppey Younes, Antoinette Pechère-Bertschi, Georg Ehret, Michel Burnier
Rok vydání: 2016
Předmět:
Zdroj: Nutrition & metabolism, vol. 13, pp. 81
Petrovic, Dusan; Estoppey Younes, Sandrine; Pruijm, Menno; Ponte, Belén; Ackermann, Daniel; Ehret, Georg; Ansermot, Nicolas; Mohaupt, Markus; Paccaud, Fred; Vogt, Bruno; Pechère-Bertschi, Antoinette; Martin, Pierre-Yves; Burnier, Michel; Eap, Chin B; Bochud, Murielle; Guessous, Idris (2016). Relation of 24-hour urinary caffeine and caffeine metabolite excretions with self-reported consumption of coffee and other caffeinated beverages in the general population. Nutrition & metabolism, 13(81), p. 81. BioMed Central 10.1186/s12986-016-0144-4
Nutrition & Metabolism, Vol. 13 (2016) P. 81
Nutrition & Metabolism
ISSN: 1743-7075
Popis: Background Caffeine intake is generally estimated by self-reported consumption, but it remains unclear how well self-report associates with metabolite urinary excretion. We investigated the associations of self-reported consumption of caffeinated drinks with urinary excretion of caffeine and its major metabolites in an adult population. Methods We used data from the population-based Swiss Kidney Project on Genes in Hypertension (SKIPOGH) study. Consumption of caffeinated coffee, decaffeinated coffee and other caffeinated beverages was assessed by self-administered questionnaire. Quantification of caffeine, paraxanthine, theobromine and theophylline was performed by ultra-high performance liquid chromatography tandem mass spectrometry in 24-h urine. Association of reported consumption of caffeinated drinks with urinary caffeine derived metabolites was determined by quantile regression. We then explored the association between urinary metabolite excretion and dichotomized weekly consumption frequency of caffeinated coffee, with Receiver Operator Characteristic (ROC) analysis. Results In the present analysis, we included 598 individuals (52% women, mean age =46 ± 17 years). Self-reported caffeinated coffee intake was positively associated with 24-h urinary excretions of paraxanthine, theophylline and caffeine (p
Databáze: OpenAIRE
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