Relation of 24-hour urinary caffeine and caffeine metabolite excretions with self-reported consumption of coffee and other caffeinated beverages in the general population
Autor: | Fred Paccaud, Pierre-Yves Martin, Idris Guessous, Murielle Bochud, Markus G. Mohaupt, Belen Ponte, Daniel Ackermann, Menno Pruijm, Dusan Petrovic, Bruno Vogt, Chin B. Eap, Nicolas Ansermot, Sandrine Estoppey Younes, Antoinette Pechère-Bertschi, Georg Ehret, Michel Burnier |
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Rok vydání: | 2016 |
Předmět: |
Paraxanthine
Endocrinology Diabetes and Metabolism Metabolite Population Medicine (miscellaneous) Physiology 610 Medicine & health Urine Population-based 030204 cardiovascular system & hematology Pharmacology Excretion 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Theophylline Caffeine Urinary excretion medicine 030212 general & internal medicine 10. No inequality education Theobromine ddc:613 ddc:616 2. Zero hunger education.field_of_study Nutrition and Dietetics Questionnaire business.industry Research 3. Good health chemistry business medicine.drug |
Zdroj: | Nutrition & metabolism, vol. 13, pp. 81 Petrovic, Dusan; Estoppey Younes, Sandrine; Pruijm, Menno; Ponte, Belén; Ackermann, Daniel; Ehret, Georg; Ansermot, Nicolas; Mohaupt, Markus; Paccaud, Fred; Vogt, Bruno; Pechère-Bertschi, Antoinette; Martin, Pierre-Yves; Burnier, Michel; Eap, Chin B; Bochud, Murielle; Guessous, Idris (2016). Relation of 24-hour urinary caffeine and caffeine metabolite excretions with self-reported consumption of coffee and other caffeinated beverages in the general population. Nutrition & metabolism, 13(81), p. 81. BioMed Central 10.1186/s12986-016-0144-4 Nutrition & Metabolism, Vol. 13 (2016) P. 81 Nutrition & Metabolism |
ISSN: | 1743-7075 |
Popis: | Background Caffeine intake is generally estimated by self-reported consumption, but it remains unclear how well self-report associates with metabolite urinary excretion. We investigated the associations of self-reported consumption of caffeinated drinks with urinary excretion of caffeine and its major metabolites in an adult population. Methods We used data from the population-based Swiss Kidney Project on Genes in Hypertension (SKIPOGH) study. Consumption of caffeinated coffee, decaffeinated coffee and other caffeinated beverages was assessed by self-administered questionnaire. Quantification of caffeine, paraxanthine, theobromine and theophylline was performed by ultra-high performance liquid chromatography tandem mass spectrometry in 24-h urine. Association of reported consumption of caffeinated drinks with urinary caffeine derived metabolites was determined by quantile regression. We then explored the association between urinary metabolite excretion and dichotomized weekly consumption frequency of caffeinated coffee, with Receiver Operator Characteristic (ROC) analysis. Results In the present analysis, we included 598 individuals (52% women, mean age =46 ± 17 years). Self-reported caffeinated coffee intake was positively associated with 24-h urinary excretions of paraxanthine, theophylline and caffeine (p |
Databáze: | OpenAIRE |
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