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Background: Acute kidney injury (AKI) associated with COVID-19 is a frequent complication that increases the severity of the viral infection and the possibility of death of the patients. Objective: To determine the incidence, clinical course, and outcome of AKI in patients with COVID-19 disease during their stay in the Intensive Care Unit (ICU). Material and methods: Retrospective cross-sectional study in a cohort of 141 COVID-19 patients from the ICU of a High Specialty Medical Unit (Infectious Diseases Hospital) during 2020 and 2021. The incidence of AKI was studied (K-DIGO criteria, 2012), clinical course, need for hemodialysis and mortality. Data were analyzed with descriptive statistics and inferential statistics (chi-square, paired Student's t-test). The p value Results: The mean baseline creatinine of the 141 patients increased during their stay in the ICU (p=0.015). The frequency of AKI was 48.22% (n=68/141). The patients with AKI had higher concentrations on admission (p=0.002) and during their stay (p=0.007). Regarding the total, only 44.68% of the patients (n=63/141) received hemodialysis, but it represented the majority of the cases with AKI (92.64%, n=63/68). The mortality of patients on hemodialysis was 79.36% (n=50/63), it was higher than general mortality 57.44% (n=81/141), the proportion was 1.62. Conclusion: AKI related to COVID-19 disease has a high incidence with the requirement of hemodialysis in almost all cases and a high percentage of mortality. Keywords: Acute kidney injury related to COVID-19; Acute kidney injury; COVID-19 pandemic; SARS-CoV2 virus infection; Hemodialysis; Critical care in infectious diseases. |
