Tru-cut biopsy of palpable breast lesions: a cpractical option for pre-operative diagnosis in developing countries
| Autor: | J T Momoh, P O Obekpa, I. D. Gukas, C H Ihezue, E. J. C. Nwana |
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| Jazyk: | angličtina |
| Rok vydání: | 2000 |
| Předmět: |
Waiting time
medicine.medical_specialty Biopsy Nigeria Sensitivity and Specificity Hospitals University Breast Diseases Histological diagnosis Preoperative Care medicine Humans Prospective Studies Trucut biopsy Developing Countries medicine.diagnostic_test business.industry General Medicine Predictive value Pre operative Cross-Sectional Studies Needle biopsy Feasibility Studies Female False positive rate Radiology business |
| Zdroj: | Central African Journal of Medicine; Vol 46, No 5 (2000) |
| ISSN: | 0008-9176 |
| Popis: | OBJECTIVES To establish the role of Tru-cut needle biopsy in the pre-operative diagnosis of breast lesions in a developing country. DESIGN Prospective cross sectional study. SUBJECTS 112 consecutive patients with palpable breast lesions who had both Tru-cut and excision biopsy as a pre-operative diagnostic procedure. RESULTS Four (3.6%) patients had specimens that were inadequate for histological diagnosis. Tru-cut biopsy diagnosed 42 of the remaining 108 as malignant and 66 as benign, but only 40 and 61 respectively were confirmed to be correctly so by excision biopsy. Tru-cut biopsy, therefore, achieved a sensitivity of 88.9% (95% CI 79.7 to 98.1) specificity of 96.8% (95% CI 92.5 to 100) and an over all diagnostic accuracy of 93.5% (95% CI 88.9 to 98.2). There was a false positive rate of 4.8%, a false negative rate of 7.6% and a positive predictive value of 95.2%. The pathologist was able to make a correct specific histological diagnosis in 76.2% of all the adequate Tru-cut samples. CONCLUSION If Tru-cut biopsy is done instead of excision biopsy, it will sufficiently reduce waiting time and reduce cost (four fold). It is well tolerated by patients. We regard the procedure as a useful adjunct and indeed a practical option for accurate pre-operative diagnosis of palpable breast lesions. |
| Databáze: | OpenAIRE |
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