Is omitting the 3rd hour measurement in the 100 g oral glucose tolerance test feasible?
| Autor: | Mehmet Murat Seval, Zihni Karaeren, Batuhan Özmen, Ibrahim Yalcin, Feride Söylemez, Yavuz Emre Şükür, Acar Koç |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Blood Glucose Plasma Glucose Measurement medicine.medical_specialty Time Factors endocrine system diseases 030209 endocrinology & metabolism Gastroenterology Plasma glucose level Cohort Studies 03 medical and health sciences 0302 clinical medicine Pregnancy Internal medicine Diabetes mellitus medicine Humans Glucose challenge test Diagnostic Errors Oral glucose tolerance Retrospective Studies 030219 obstetrics & reproductive medicine business.industry nutritional and metabolic diseases Obstetrics and Gynecology Glucose Tolerance Test medicine.disease Gestational diabetes Diabetes Gestational Pediatrics Perinatology and Child Health Feasibility Studies Female business |
| Zdroj: | Journal of Perinatal Medicine. 44 |
| ISSN: | 1619-3997 0300-5577 |
| DOI: | 10.1515/jpm-2015-0124 |
| Popis: | Background To evaluate the diagnostic value of the 3rd hour plasma glucose level in the 100 g oral glucose tolerance test (OGTT). Methods Records of all pregnant patients with abnormal 50 g glucose challenge test (GCT) between January 2005 and December 2013 were reviewed (n=1963). The 100 g OGTT results were analyzed separately for both Carpenter & Couston (CC) and National Diabetes Data Group (NDDG) criteria. Results The number of patients diagnosed with gestational diabetes mellitus (GDM) was 297 (15.1%) according to CC criteria and 166 (8.4%) according to NDDG criteria. The 1st hour plasma glucose level showed the highest correlation with GDM diagnosis (ρ=0.595 for CC and ρ=0.567 for NDDG). However, the 3rd hour plasma glucose level showed the weakest correlation with GDM diagnosis (ρ=0.216 for CC and ρ=0.213 for NDDG). The 3rd hour value of 100 g OGTT was one of the two elevated measurements in 10.8% of patients when CC criteria are used and in 13.8% of patients when NDDG criteria are used. Conclusion Omitting 3rd hour plasma glucose measurement in 100 g OGTT results in unacceptable rates of underdiagnosed patients. |
| Databáze: | OpenAIRE |
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