Single nucleotide polymorphism and lifestyle-related diseases in the Asia-Pacific region: comparative study in Okinawa, Palau and Thailand

Autor: Yasuo Kagawa, Phitaya Charupoonphol, G J Dever, S Supannatas, Kyoko Hasegawa, C T Y Otto, Yoshiko Yanagisawa, Mitsuru Sakuma
Rok vydání: 2008
Předmět:
Apolipoprotein E
Male
medicine.medical_specialty
Asia
Population
Peroxisome Proliferator-Activated Receptors
Angiotensinogen
Gene Expression
030209 endocrinology & metabolism
Single-nucleotide polymorphism
Blood Pressure
Biology
Pacific Islands
Polymorphism
Single Nucleotide

Ion Channels
White People
Body Mass Index
Mitochondrial Proteins
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Apolipoproteins E
Asian People
Polymorphism (computer science)
Internal medicine
medicine
Uncoupling protein
Humans
Uncoupling Protein 3
Uncoupling Protein 2
030212 general & internal medicine
education
Life Style
Aged
education.field_of_study
Leptin receptor
Triglyceride
Public Health
Environmental and Occupational Health

Middle Aged
Lipids
Endocrinology
chemistry
Receptors
Adrenergic
beta-3

Chronic Disease
Receptors
Leptin

Female
Body mass index
Zdroj: Asia-Pacific journal of public health.
ISSN: 1010-5395
Popis: Genetic differences between Asians and Caucasians may be involved in the rapid increase in lifestyle-related diseases in the Asia-Pacific region that has coincided with Westernisation of diets in the region. In the present study, we assessed correlation between 10 single nucleotide polymorphisms (SNPs) and chronic disease risk factors in age-matched and population-based groups in four Asian-Pacific locations: Okinawa, Palau and Thailand (two areas). The following allelic SNP profiles significantly differed (p
Databáze: OpenAIRE