The Effect of Glutamine-Enriched Enteral Nutrition on Intestinal Permeability in Very-Low-Birth-Weight Infants: A Randomized Controlled Trial

Autor: Hilda R. A. van der Molen, Ina M. van der Vegt, Willem P. F. Fetter, Anemone van den Berg, Elisabeth A. M. Westerbeek, Ruurd M. van Elburg
Přispěvatelé: Other departments, Faculteit Medische Wetenschappen/UMCG
Rok vydání: 2006
Předmět:
Male
Pediatrics
Time Factors
030309 nutrition & dietetics
Glutamine
Medicine (miscellaneous)
Gastroenterology
Enteral administration
Lactulose
0302 clinical medicine
BACTERIAL TRANSLOCATION
INFECTIOUS MORBIDITY
FETAL BLOOD
Infant
Very Low Birth Weight
Mannitol
Infant Nutritional Physiological Phenomena
0303 health sciences
Nutrition and Dietetics
PARENTERAL-NUTRITION
Gestational age
Treatment Outcome
Female
030211 gastroenterology & hepatology
medicine.symptom
CRITICALLY-ILL PATIENTS
medicine.drug
medicine.medical_specialty
Birth weight
Permeability
03 medical and health sciences
Enteral Nutrition
Double-Blind Method
PRETERM INFANTS
Internal medicine
medicine
Humans
HUMAN-MILK
Intestinal permeability
business.industry
INTRAUTERINE GROWTH
GUT PERMEABILITY
Infant
Newborn
medicine.disease
Low birth weight
Parenteral nutrition
Intestinal Absorption
BARRIER FUNCTION
business
Zdroj: JPEN. Journal of parenteral and enteral nutrition, 30(5), 408-414. SAGE Publications Inc.
Journal of Parenteral and Enteral Nutrition, 30(5), 408-414. Wiley
ISSN: 1941-2444
0148-6071
DOI: 10.1177/0148607106030005408
Popis: Background: Very-low-birth-weight (VLBW) infants are susceptible to glutamine depletion. Glutamine depletion has negative effects on intestinal integrity. The lower infection rate in VLBW infants receiving glutamine-enriched enteral nutrition may originate from improved intestinal integrity, as reflected by decreased intestinal permeability. The aim of our study was to investigate whether glutamine-enriched enteral nutrition in VLBW infants enhances the normal decrease in intestinal permeability, as measured by the sugar absorption test (SAT). Methods: In a double-blind, randomized, placebo-controlled trial, VLBW infants (gestational age
Databáze: OpenAIRE
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