Acoustic analysis of voice in multiple sclerosis patients
| Autor: | Sérgio Haussen, Adriana Vélez Feijó, Maria Cecı́lia De Veccino, Beatriz Castellar de Faria Martignago, Mara Behlau, Maria Alice de Mattos Pimenta Parente |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Multiple Sclerosis Sound Spectrography Voice Quality Cross-sectional study Audiology Speech Acoustics Speech and Hearing symbols.namesake Speech Production Measurement Statistical significance Internal medicine medicine Humans Yates's correction for continuity Fisher's exact test Chi-Square Distribution Hoarseness Voice Disorders business.industry Multiple sclerosis Respiratory disease Case-control study Middle Aged LPN and LVN medicine.disease Cross-Sectional Studies Otorhinolaryngology Case-Control Studies Voice symbols Female business Chi-squared distribution |
| Zdroj: | Journal of Voice. 18:341-347 |
| ISSN: | 0892-1997 |
| DOI: | 10.1016/j.jvoice.2003.05.004 |
| Popis: | The objective is to investigate the presence of dysphonic symptoms in multiple sclerosis (MS) patients and to compare quantitative acoustic parameters in multiple sclerosis patients and normal individuals. The method of study was an 8-month controlled cross-sectional that was carried out with 106 individuals (30 MS, 76 controls). Both groups included males and females from 20 to 55 years. Exclusion criteria were prior vocal disorder, laryngeal microsurgery, recent endotracheal intubation, tumors, laryngeal, lung or mediastinal metastases, respiratory disease, and other associated neurological diagnoses. For dysphonic symptoms (qualitative variables), associations were assessed using Mantel-Haenszel's chi2 test, with Yates correction or the Fisher exact test when necessary. Statistical significance was set at p< or =0.05. Dysphonia was observed in 70% of MS individuals versus 33% of controls (p=0.01). Association was found between MS and dysphonia (OR: 2.2, CI 95%: 1.13-4.25). Fundamental frequency was higher among MS patients (p=0.01). Fundamental frequency deviation was significantly higher in MS women (but not men) than controls (p=0.00). Jitter was higher in MS men than in all other groups (p=0.00). Results suggest that evaluation and treatment of MS patients should be revised, evaluating voice alterations in relation to other signs. MS seems to intensify gender effect on fundamental frequency deviation, noise, and jitter, with MS women presenting fewer voice variations than men. |
| Databáze: | OpenAIRE |
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